PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14601136-3 2003 Our specific hypothesis was that phenylalanine hydroxylase (PAH) expressed in bone marrow would lower blood phenylalanine levels in hyperphenylalaninemic Pah(enu2) mice, a model of human phenylketonuria (PKU). p-Aminohippuric Acid 154-157 phenylalanine hydroxylase Mus musculus 33-58 29648495-1 2019 Mice that were heterozygous dominant for the enu1 and enu2 mutation in phenylalanine monooxygenase/phenylalanine hydroxylase (PAH) resulted in hepatic PAH assays for S-carboxymethyl-L-cysteine (SCMC) that had significantly increased calculated Km (wild type (wt)/enu1, 1.84-2.12 fold increase and wt/enu2 a 2.75 fold increase in PAH assays). p-Aminohippuric Acid 126-129 phenylalanine hydroxylase Mus musculus 99-124 29648495-1 2019 Mice that were heterozygous dominant for the enu1 and enu2 mutation in phenylalanine monooxygenase/phenylalanine hydroxylase (PAH) resulted in hepatic PAH assays for S-carboxymethyl-L-cysteine (SCMC) that had significantly increased calculated Km (wild type (wt)/enu1, 1.84-2.12 fold increase and wt/enu2 a 2.75 fold increase in PAH assays). p-Aminohippuric Acid 151-154 phenylalanine hydroxylase Mus musculus 99-124 29648495-1 2019 Mice that were heterozygous dominant for the enu1 and enu2 mutation in phenylalanine monooxygenase/phenylalanine hydroxylase (PAH) resulted in hepatic PAH assays for S-carboxymethyl-L-cysteine (SCMC) that had significantly increased calculated Km (wild type (wt)/enu1, 1.84-2.12 fold increase and wt/enu2 a 2.75 fold increase in PAH assays). p-Aminohippuric Acid 151-154 phenylalanine hydroxylase Mus musculus 99-124 16043102-6 2005 Conversely, transplantation of PAH-positive hepatocytes into PAH-deficient Pah(enu2) mice, a model of human PKU, yielded a significant decrease in serum phenylalanine (<700 muM) when liver repopulation exceeded approximately 5%. p-Aminohippuric Acid 75-78 phenylalanine hydroxylase Mus musculus 31-34 16043102-6 2005 Conversely, transplantation of PAH-positive hepatocytes into PAH-deficient Pah(enu2) mice, a model of human PKU, yielded a significant decrease in serum phenylalanine (<700 muM) when liver repopulation exceeded approximately 5%. p-Aminohippuric Acid 75-78 phenylalanine hydroxylase Mus musculus 61-64