PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33066667-3 2020 AhR, when binding with exogenous ligands (environmental pollutants such as polycylic aryl hydrocarbon (PAH), dioxins) or endogenous ligand indoxyl-sulfate (IS), has dual functions that are mediated by the nature of the binding ligand, binding time, and specific pathways of distinct ligands. p-Aminohippuric Acid 103-106 aryl hydrocarbon receptor Homo sapiens 0-3 7598497-2 1995 Binding of polycyclic or halogenated aromatic hydrocarbon (PAH and HAH) ligand causes release of AHR, which then associates with the AHR nuclear translocator protein (ARNT) to generate the heterodimeric "transformed" AHRC. p-Aminohippuric Acid 59-62 aryl hydrocarbon receptor Homo sapiens 97-100 15777215-3 2005 Complex interactions between PAH-mediated AhR activation and ER signalling pathways have been discovered which may contribute to the developmental malformations, impact on reproductive dysfunctions and promote carcinogenic dedifferentiation of tissues within the female reproductive tract. p-Aminohippuric Acid 29-32 aryl hydrocarbon receptor Homo sapiens 42-45 7971604-4 1994 Methods for assessment of the affinity of AHR protein to PAH which make it possible to assess human susceptibility to carcinogens have been reviewed. p-Aminohippuric Acid 57-60 aryl hydrocarbon receptor Homo sapiens 42-45 30743243-7 2019 According to the high concentrations of PAH and other related organic chemicals found in this OEM, CYP1A1 and 1B1 genes exhibited high transcription levels in BEAS-2B cells, thereby supporting both the activation of the critical AhR signaling pathway and the formation of highly reactive ultimate metabolites. p-Aminohippuric Acid 40-43 aryl hydrocarbon receptor Homo sapiens 229-232 25068070-1 2013 The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates a battery of genes in response to exposure to a broad class of environmental poly aromatic hydrocarbons (PAH). p-Aminohippuric Acid 199-202 aryl hydrocarbon receptor Homo sapiens 4-29 21486221-1 2011 The aryl hydrocarbon receptor (AhR) is a ligand activated basic helix-loop-helix transcription factor that binds to environmental poly aromatic hydrocarbons (PAH) and mediates their toxic and carcinogenic responses. p-Aminohippuric Acid 158-161 aryl hydrocarbon receptor Homo sapiens 31-34 21486221-2 2011 There is ample documentation for the role of AhR in PAH-induced carcinogenicity. p-Aminohippuric Acid 52-55 aryl hydrocarbon receptor Homo sapiens 45-48 21256954-12 2011 In conclusion, quercetin appears to have two faces, a flavonoid-like one and a PAH-like one which supports Ahr-mediated effects while kaempferol acts "just like a flavonoid". p-Aminohippuric Acid 79-82 aryl hydrocarbon receptor Homo sapiens 107-110 27816282-8 2017 Chemical analysis revealed that PAH components are correlated with AhR-binding activities. p-Aminohippuric Acid 32-35 aryl hydrocarbon receptor Homo sapiens 67-70 25068070-1 2013 The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates a battery of genes in response to exposure to a broad class of environmental poly aromatic hydrocarbons (PAH). p-Aminohippuric Acid 199-202 aryl hydrocarbon receptor Homo sapiens 31-34