PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25519733-0	2015	Brain ACE2 overexpression reduces DOCA-salt hypertension independently of endoplasmic reticulum stress.	Desoxycorticosterone Acetate	34-38	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	6-10	
25489058-2	2015	We previously reported that angiotensin-converting enzyme 2 (ACE2) overexpression in the brain attenuates the development of deoxycorticosterone acetate-salt hypertension, a neurogenic hypertension model with enhanced brain renin-angiotensin system and sympathetic activity.	Desoxycorticosterone Acetate	125-152	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	28-59	
25489058-2	2015	We previously reported that angiotensin-converting enzyme 2 (ACE2) overexpression in the brain attenuates the development of deoxycorticosterone acetate-salt hypertension, a neurogenic hypertension model with enhanced brain renin-angiotensin system and sympathetic activity.	Desoxycorticosterone Acetate	125-152	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	61-65	
25489058-6	2015	Deoxycorticosterone acetate-salt-induced reduction of neuronal nitric oxide synthase expression (-26+-7%) and phosphorylated endothelial nitric oxide synthase/total endothelial nitric oxide synthase (-30+-3%), and enhanced phosphorylation of protein kinase B and extracellular signal-regulated kinase 1/2 in the paraventricular nucleus, were reversed by ACE2 overexpression.	Desoxycorticosterone Acetate	0-27	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	354-358	
24014829-5	2013	Deoxycorticosterone acetate-salt treatment in nontransgenic mice led to significant increases in blood pressure, hypothalamic angiotensin II levels, inflammation, impaired baroreflex sensitivity, and autonomic dysfunction, as well as decreased hypothalamic ACE2 activity and expression, although these changes were blunted or prevented in syn-hACE2 mice.	Desoxycorticosterone Acetate	0-27	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	257-261	
24014829-6	2013	In addition, reduction of ACE2 expression and activity in the brain paralleled an increase in ACE2 activity in the cerebrospinal fluid of nontransgenic mice after deoxycorticosterone acetate-salt treatment and were accompanied by enhanced ADAM17 expression and activity in the hypothalamus.	Desoxycorticosterone Acetate	163-190	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	26-30	
24014829-6	2013	In addition, reduction of ACE2 expression and activity in the brain paralleled an increase in ACE2 activity in the cerebrospinal fluid of nontransgenic mice after deoxycorticosterone acetate-salt treatment and were accompanied by enhanced ADAM17 expression and activity in the hypothalamus.	Desoxycorticosterone Acetate	163-190	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	94-98