PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35348007-1 2022 Hypertension characterized by low circulating renin activity accounts for roughly 25-30% of primary hypertension in humans and can be modeled experimentally via deoxycorticosterone acetate (DOCA)-salt treatment. Desoxycorticosterone Acetate 190-194 renin Homo sapiens 46-51 35348007-1 2022 Hypertension characterized by low circulating renin activity accounts for roughly 25-30% of primary hypertension in humans and can be modeled experimentally via deoxycorticosterone acetate (DOCA)-salt treatment. Desoxycorticosterone Acetate 161-188 renin Homo sapiens 46-51 6999497-0 1980 Deoxycorticosterone acetate-induced renin suppression in the absence of antidiuretic hormone. Desoxycorticosterone Acetate 0-27 renin Homo sapiens 36-41 573464-3 1979 The juxtaglomerular renin activity and tubuloglomerular feedback response were inhibited acutely, by saline expansion, or chronically, by DOCA-treatment with saline drinking fluid or salt diet, by high salt diet alone, or by inducing two-kidney Goldblatt hypertension. Desoxycorticosterone Acetate 138-142 renin Homo sapiens 20-25 397714-2 1979 Infants with the salt-losing form had high plasma renin activity levels 5--11 months after subcutaneous implantation of a pellet containing 100 mg deoxycorticosterone acetate. Desoxycorticosterone Acetate 147-174 renin Homo sapiens 50-55 397714-3 1979 These elevated plasma renin activity levels were suppressed to the normal range by repeated implantation of DOCA pellet. Desoxycorticosterone Acetate 108-112 renin Homo sapiens 22-27 21263123-3 2011 Previous studies have demonstrated that DOCA-salt hypertension is mediated through activation of the brain renin-angiotensin system. Desoxycorticosterone Acetate 40-44 renin Homo sapiens 107-112 754801-0 1978 [Behavior of plasma renin activity (PRA) after administration of DOCA in normal subjects]. Desoxycorticosterone Acetate 65-69 renin Homo sapiens 20-25 754804-0 1978 [Blood aldosterone levels and plasma renin activity after administration of DOCA]. Desoxycorticosterone Acetate 76-80 renin Homo sapiens 37-42 1127075-0 1975 Suppression of renin and aldosterone by small amounts of DOCA in normal man. Desoxycorticosterone Acetate 57-61 renin Homo sapiens 15-20 26119848-4 2015 This is particularly important because increased oxidative stress plays a major role in the DOCA-salt hypertension model, which is less dependent on activation of the renin-angiotensin system than other hypertension models. Desoxycorticosterone Acetate 92-96 renin Homo sapiens 167-172