PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30087941-0	2018	Drug-Carrying Capacity and Anticancer Effect of the Folic Acid- and Berberine-Loaded Silver Nanomaterial To Regulate the AKT-ERK Pathway in Breast Cancer.	Folic Acid	52-62	AKT serine/threonine kinase 1	Homo sapiens	121-124	
27682214-0	2016	Aerosol delivery of folate-decorated hyperbranched polyspermine complexes to suppress lung tumorigenesis via Akt signaling pathway.	Folic Acid	20-26	AKT serine/threonine kinase 1	Homo sapiens	109-112	
29376449-6	2018	In KB cells, uptake and Akt1 inhibition by F-LAN-RX-0201 were greater than those of non-targeted LAN-RX-0201 and could be partially blocked by excess free folate.	Folic Acid	155-161	AKT serine/threonine kinase 1	Homo sapiens	24-28	
23796957-11	2013	Inhibition of PI3K/Akt revealed specific roles for this kinase pathway in folic acid-mediated eNOS phosphorylation.	Folic Acid	74-84	AKT serine/threonine kinase 1	Homo sapiens	19-22	
27113042-11	2016	These findings demonstrated that folic acid protected neuronal cells against Al-malt-induced apoptosis by preventing the downregulation of miR-19 and modulation of miR-19 related downstream PTEN/AKT/p53 pathway.	Folic Acid	33-43	AKT serine/threonine kinase 1	Homo sapiens	195-198	
26974319-0	2016	Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1alpha Pathway.	Folic Acid	0-10	AKT serine/threonine kinase 1	Homo sapiens	96-99	
26974319-7	2016	Folic acid also reduced hypoxia-induced Akt phosphorylation and decreased nuclear accumulation of HIF-1alpha protein.	Folic Acid	0-10	AKT serine/threonine kinase 1	Homo sapiens	40-43	
26974319-9	2016	We also found that insulin (an Akt activator) and dimethyloxallyl glycine (DMOG, a HIF-1alpha activator) induced over-expression of inflammatory cytokines, which could be blocked by folic acid.	Folic Acid	182-192	AKT serine/threonine kinase 1	Homo sapiens	31-34	
26974319-10	2016	Taken together, these findings demonstrate how folic acid attenuates the hypoxia-induced inflammatory responses of THP-1 cells through inhibition of the PI3K/Akt/HIF-1alpha pathway.	Folic Acid	47-57	AKT serine/threonine kinase 1	Homo sapiens	158-161	
21640799-11	2011	In conclusion, the results of this study show that folic acid can protect against dexamethasone-induced neurotoxicity and its protective mechanism is related to a signaling pathway that involves PI3K/Akt, CaMKII, and PKA.	Folic Acid	51-61	AKT serine/threonine kinase 1	Homo sapiens	200-203	
18830563-4	2008	By using a natural stable folate we were able to reverse the EGCG suppression of TNF-alpha-induced NF-kappaB activation, the phosphorylation and degradation of IkappaBalpha and the phosphorylation of Akt in this human colon carcinoma cell line.	Folic Acid	26-32	AKT serine/threonine kinase 1	Homo sapiens	200-203	
19640582-0	2009	The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway.	Folic Acid	59-65	AKT serine/threonine kinase 1	Homo sapiens	98-102	
19640582-0	2009	The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway.	Folic Acid	59-65	AKT serine/threonine kinase 1	Homo sapiens	98-101