PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22303332-10	2011	Tissue MTHFS protein levels are decreased in both Mthfs(gt/+) and Mthfs(+/+) mice placed on a folate and choline deficient diet, and mouse embryonic fibroblasts from Mthfs(gt/+) embryos exhibit decreased capacity for de novo purine synthesis without impairment in de novo thymidylate synthesis.	Folic Acid	94-100	5, 10-methenyltetrahydrofolate synthetase	Mus musculus	7-12	
17250800-3	2007	Folate analogs that cannot undergo the rate-limiting step in catalysis were inhibitors of murine MTHFS.	Folic Acid	0-6	5, 10-methenyltetrahydrofolate synthetase	Mus musculus	97-102	
15135403-3	2004	The enzyme 5,10-methenyltetrahydrofolate synthetase (MTHFS, EC 6.3.3.2) catalyzes the ATP-dependent conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, and has been shown to affect intracellular folate concentrations by accelerating folate degradation.	Folic Acid	34-40	5, 10-methenyltetrahydrofolate synthetase	Mus musculus	53-58	
15135403-3	2004	The enzyme 5,10-methenyltetrahydrofolate synthetase (MTHFS, EC 6.3.3.2) catalyzes the ATP-dependent conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, and has been shown to affect intracellular folate concentrations by accelerating folate degradation.	Folic Acid	132-138	5, 10-methenyltetrahydrofolate synthetase	Mus musculus	11-51	
15135403-3	2004	The enzyme 5,10-methenyltetrahydrofolate synthetase (MTHFS, EC 6.3.3.2) catalyzes the ATP-dependent conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, and has been shown to affect intracellular folate concentrations by accelerating folate degradation.	Folic Acid	132-138	5, 10-methenyltetrahydrofolate synthetase	Mus musculus	53-58