PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29255930-10	2019	CONCLUSION: Folic acid supplementation appears to improve cognitive function and reduce blood levels of Abeta-related biomarkers in MCI.	Folic Acid	12-22	amyloid beta precursor protein	Homo sapiens	104-109	
33749643-12	2021	CONCLUSION: Folic acid and DHA improve cognitive function and reduce blood Abeta production in MCI patients.	Folic Acid	12-22	amyloid beta precursor protein	Homo sapiens	75-80	
35233817-11	2022	CONCLUSION: Lower masticatory performance, lower SSF and fewer teeth were associated with a lower intake of several micronutrients, such as vitamin A, beta-carotene and folic acids, in Japanese individuals of advanced age.	Folic Acid	169-180	amyloid beta precursor protein	Homo sapiens	90-91	
28406978-11	2017	These results suggest that a deficiency of serum folate and high hemoglobin levels may reflect an increased risk of amyloid beta accumulation in the brain.	Folic Acid	49-55	amyloid beta precursor protein	Homo sapiens	116-128	
28406978-13	2017	This study reveals that the combined assessment of serum folate levels and red blood cell hemoglobin content may be a useful biomarker for amyloid beta accumulation in the brain.	Folic Acid	57-63	amyloid beta precursor protein	Homo sapiens	139-151	
21205217-0	2011	Genistein and folic acid prevent oxidative injury induced by beta-amyloid peptide.	Folic Acid	14-24	amyloid beta precursor protein	Homo sapiens	61-81	
15607954-4	2005	Here we demonstrate that BACE (beta-secretase), as well as PS1, is regulated by methylation and that the reduction of folate and vitamin B12 in culture medium can cause a reduction of SAM levels with consequent increase in presenilin1 and BACE levels and with increase in A beta production.	Folic Acid	118-124	amyloid beta precursor protein	Homo sapiens	272-278	
14624028-3	2003	Indeed, folate deprivation, which has been associated with AD, potentiates generation of reactive oxygen species (ROS) by Abeta.	Folic Acid	8-14	amyloid beta precursor protein	Homo sapiens	122-127	
14624028-5	2003	Folate-deprivation and Abeta treatment each induced an increase in ROS, and treatment of folate-deprived cultures with Abeta induced a synergistic increase in ROS.	Folic Acid	89-95	amyloid beta precursor protein	Homo sapiens	119-124	
14624028-6	2003	17-beta-estradiol reduced ROS levels in beta-treated, folate-deprived cultures to ROS levels observed in cultures treated with Abeta in the presence of folate, suggesting that this antioxidant was able to prevent the synergistic impact of Abeta and folate deprivation on ROS generation.	Folic Acid	54-60	amyloid beta precursor protein	Homo sapiens	239-244	
14624028-6	2003	17-beta-estradiol reduced ROS levels in beta-treated, folate-deprived cultures to ROS levels observed in cultures treated with Abeta in the presence of folate, suggesting that this antioxidant was able to prevent the synergistic impact of Abeta and folate deprivation on ROS generation.	Folic Acid	152-158	amyloid beta precursor protein	Homo sapiens	127-132	
14624028-6	2003	17-beta-estradiol reduced ROS levels in beta-treated, folate-deprived cultures to ROS levels observed in cultures treated with Abeta in the presence of folate, suggesting that this antioxidant was able to prevent the synergistic impact of Abeta and folate deprivation on ROS generation.	Folic Acid	152-158	amyloid beta precursor protein	Homo sapiens	127-132	
11880504-3	2002	Incubation of hippocampal cultures in folic acid-deficient medium or in the presence of methotrexate (an inhibitor of folic acid metabolism) or homocysteine induced cell death and rendered neurons vulnerable to death induced by Abeta.	Folic Acid	38-48	amyloid beta precursor protein	Homo sapiens	228-233