PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12091352-2 2002 To identify a receptor tyrosine kinase (RTK) inhibitor capable of blocking the function of mutant Kit, we evaluated 3 indolinones (SU11652, SU11654, and SU11655) that act as competitive inhibitors of adenosine triphosphate binding to several members of the split kinase family of RTKs, including VEGFR, FGFR, PDGFR, and Kit. SU 11652 131-138 ret proto-oncogene Homo sapiens 40-43 12091352-7 2002 In summary, SU11652, SU11654, and SU11655 are effective RTK inhibitors capable of disrupting the function of all forms of mutant Kit. SU 11652 12-19 ret proto-oncogene Homo sapiens 56-59