PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26424893-12 2015 Significance statement: In this original work, it is shown for the first time that paclitaxel activates peripheral sensory and spinal neurons directly and sensitizes these cells to transient receptor potential vanilloid subtype 1 (TRPV1)-mediated capsaicin responses via Toll-like receptor 4 (TLR4) in multiple species. Capsaicin 247-256 toll like receptor 4 Homo sapiens 271-291 26424893-12 2015 Significance statement: In this original work, it is shown for the first time that paclitaxel activates peripheral sensory and spinal neurons directly and sensitizes these cells to transient receptor potential vanilloid subtype 1 (TRPV1)-mediated capsaicin responses via Toll-like receptor 4 (TLR4) in multiple species. Capsaicin 247-256 toll like receptor 4 Homo sapiens 293-297 25139109-8 2014 Heterologous expression experiments in HEK293T cells indicated that TLR4 expression enhanced capsaicin-induced intracellular calcium signals and inward currents. Capsaicin 93-102 toll like receptor 4 Homo sapiens 68-72 16373680-5 2006 Collectively, these studies indicate that the capsaicin-sensitive subclass of trigeminal nociceptors expresses TLR4 and CD14. Capsaicin 46-55 toll like receptor 4 Homo sapiens 111-115