PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24643130-3	2014	Here, we reported that capsaicin had a profound anti-proliferative effect on human colon cancer cells via inducing cell cycle G0/G1 phase arrest and apoptosis, which was associated with an increase of p21, Bax and cleaved PARP.	Capsaicin	23-32	H3 histone pseudogene 16	Homo sapiens	201-204	
20646592-5	2010	And the expressions of cell cycle protein P53, P21, CDK2 were detected by Western blot after the treatment of capsaicin.	Capsaicin	110-119	H3 histone pseudogene 16	Homo sapiens	47-50	
20646592-11	2010	After a 48-hour treatment with capsaicin, the expressions of P53 and P21 were up-regulated in contrary to the expression of CDK2.	Capsaicin	31-40	H3 histone pseudogene 16	Homo sapiens	69-72	
20646592-12	2010	CONCLUSION: Capsaicin induces the cell cycle arrest of bladder cancer RT4 cells G(0)/G(1) phase and growth inhibition via TRPV1 receptor by modulating the expression of P53, P21 and CDK2.	Capsaicin	12-21	H3 histone pseudogene 16	Homo sapiens	174-177	
16942782-6	2006	Capsaicin induced G0-G1 phase arrest underwent the promotion of p53 and p21, which is an inhibitor of Cdk2 and cyclin E complex before leading to the inhibitions of both compounds.	Capsaicin	0-9	H3 histone pseudogene 16	Homo sapiens	72-75	
19139269-4	2009	Exposure to capsaicin or DHC caused induction of p53, p21, and G(0)/G(1) arrest.	Capsaicin	12-21	H3 histone pseudogene 16	Homo sapiens	54-57	
35405615-11	2022	Capsaicin upregulated SIRT1 expression and downregulated the senescence marker, p21, thereby protecting endothelial cells from IHG-induced senescence as indicated by relieved G0/G1 phase arrest, improved cell viabilities, and reduced counts of senescent cells and ROS production.	Capsaicin	0-9	H3 histone pseudogene 16	Homo sapiens	80-83