PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18985006-0 2008 Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway. Capsaicin 21-30 thymoma viral proto-oncogene 1 Mus musculus 104-107 18985006-5 2008 Although B16-F10 cell migration was increased by the PI3-K activator through the activation of Akt, these PI3-K activator-induced phenomena were attenuated by capsaicin. Capsaicin 159-168 thymoma viral proto-oncogene 1 Mus musculus 95-98 18985006-7 2008 These results demonstrate that capsaicin inhibits the migration of B16-F10 cells through the inhibition of the PI3-K/Akt/Rac1 signal pathway. Capsaicin 31-40 thymoma viral proto-oncogene 1 Mus musculus 117-120 18985006-8 2008 The present investigation suggests that capsaicin targets PI3-K/Akt/ Rac1-mediated cellular events in B16-F10 melanoma cells. Capsaicin 40-49 thymoma viral proto-oncogene 1 Mus musculus 64-67 34703269-0 2021 Capsaicin Protects Against Lipopolysaccharide-Induced Acute Lung Injury Through the HMGB1/NF-kappaB and PI3K/AKT/mTOR Pathways. Capsaicin 0-9 thymoma viral proto-oncogene 1 Mus musculus 109-112 32293931-10 2020 Bumetanide, A889425 and the Akt inhibitor Akti prevented the Rb+ uptake response to capsaicin. Capsaicin 84-93 thymoma viral proto-oncogene 1 Mus musculus 28-31 20660715-8 2010 TPA/capsaicin cotreatment caused EGFR tyrosine phosphorylation and activated EGFR downstream signaling, including ERKs and Akt in EGFR/WT, but not EGFR/KO cells. Capsaicin 4-13 thymoma viral proto-oncogene 1 Mus musculus 123-126