PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12586218-0 2003 Transforming growth factor alpha-mediated gastroprotection against stress ulceration in the rat: involvement of capsaicin-sensitive sensory neurons. Capsaicin 112-121 transforming growth factor alpha Rattus norvegicus 0-32 15120476-7 2004 Both CGRP (1 x 10(-7) to 1 x 10(-5) M) and capsaicin (1 x 10-(8) to 1 x 10(-6)M) significantly inhibited basal TGFalpha release in a dose-dependent fashion that ranged from -20% to -39%. Capsaicin 43-52 transforming growth factor alpha Rattus norvegicus 111-119 15120476-8 2004 In contrast, capsaicin-induced sensory denervation caused significant increases in both basal TGFalpha release and TGFalpha tissue content. Capsaicin 13-22 transforming growth factor alpha Rattus norvegicus 94-102 15120476-8 2004 In contrast, capsaicin-induced sensory denervation caused significant increases in both basal TGFalpha release and TGFalpha tissue content. Capsaicin 13-22 transforming growth factor alpha Rattus norvegicus 115-123 15120476-9 2004 CONCLUSION: Function interactions between TGFalpha and gastric sensory neurons are suggested by the observations that (1) TGFalpha stimulated CGRP release from gastric sensory neurons; (2) CGRP and acute capsaicin treatment inhibited TGFalpha release and; (3) capsaicin-induced sensory denervation caused significant increases in both gastric TGFalpha basal release and tissue content. Capsaicin 204-213 transforming growth factor alpha Rattus norvegicus 42-50 15120476-9 2004 CONCLUSION: Function interactions between TGFalpha and gastric sensory neurons are suggested by the observations that (1) TGFalpha stimulated CGRP release from gastric sensory neurons; (2) CGRP and acute capsaicin treatment inhibited TGFalpha release and; (3) capsaicin-induced sensory denervation caused significant increases in both gastric TGFalpha basal release and tissue content. Capsaicin 260-269 transforming growth factor alpha Rattus norvegicus 42-50 15120476-9 2004 CONCLUSION: Function interactions between TGFalpha and gastric sensory neurons are suggested by the observations that (1) TGFalpha stimulated CGRP release from gastric sensory neurons; (2) CGRP and acute capsaicin treatment inhibited TGFalpha release and; (3) capsaicin-induced sensory denervation caused significant increases in both gastric TGFalpha basal release and tissue content. Capsaicin 260-269 transforming growth factor alpha Rattus norvegicus 122-130 15120476-9 2004 CONCLUSION: Function interactions between TGFalpha and gastric sensory neurons are suggested by the observations that (1) TGFalpha stimulated CGRP release from gastric sensory neurons; (2) CGRP and acute capsaicin treatment inhibited TGFalpha release and; (3) capsaicin-induced sensory denervation caused significant increases in both gastric TGFalpha basal release and tissue content. Capsaicin 260-269 transforming growth factor alpha Rattus norvegicus 122-130 15120476-9 2004 CONCLUSION: Function interactions between TGFalpha and gastric sensory neurons are suggested by the observations that (1) TGFalpha stimulated CGRP release from gastric sensory neurons; (2) CGRP and acute capsaicin treatment inhibited TGFalpha release and; (3) capsaicin-induced sensory denervation caused significant increases in both gastric TGFalpha basal release and tissue content. Capsaicin 260-269 transforming growth factor alpha Rattus norvegicus 122-130 12586218-14 2003 We conclude that: 1) TGF alpha caused dose-dependent gastroprotection against WRS ulceration, 2) TGF alpha-mediated gastric mucosal protection was prevented by capsaicin-induced sensory denervation and, 3) stress-induced injury was associated with significant reduction in gastric content of both TGF alpha and CGRP. Capsaicin 160-169 transforming growth factor alpha Rattus norvegicus 21-30 12586218-14 2003 We conclude that: 1) TGF alpha caused dose-dependent gastroprotection against WRS ulceration, 2) TGF alpha-mediated gastric mucosal protection was prevented by capsaicin-induced sensory denervation and, 3) stress-induced injury was associated with significant reduction in gastric content of both TGF alpha and CGRP. Capsaicin 160-169 transforming growth factor alpha Rattus norvegicus 97-106 12586218-14 2003 We conclude that: 1) TGF alpha caused dose-dependent gastroprotection against WRS ulceration, 2) TGF alpha-mediated gastric mucosal protection was prevented by capsaicin-induced sensory denervation and, 3) stress-induced injury was associated with significant reduction in gastric content of both TGF alpha and CGRP. Capsaicin 160-169 transforming growth factor alpha Rattus norvegicus 97-106 11989832-0 2002 Capsaicin-sensitive nerve fibres induce epithelial cell proliferation, inflammatory cell immigration and transforming growth factor-alpha expression in the rat colonic mucosa in vivo. Capsaicin 0-9 transforming growth factor alpha Rattus norvegicus 105-137 11989832-2 2002 The aim of our study was to evaluate the effects of capsaicin-sensitive nerve fibres in rat colonic mucosa on epithelial cell proliferation and transforming growth factor-alpha (TGFalpha) expression, which is important in mucosal defence, protection and repair. Capsaicin 52-61 transforming growth factor alpha Rattus norvegicus 144-176 11989832-2 2002 The aim of our study was to evaluate the effects of capsaicin-sensitive nerve fibres in rat colonic mucosa on epithelial cell proliferation and transforming growth factor-alpha (TGFalpha) expression, which is important in mucosal defence, protection and repair. Capsaicin 52-61 transforming growth factor alpha Rattus norvegicus 178-186 11989832-10 2002 A 2-fold increase of TGFalpha mRNA and a 10-fold increase of TGFalpha protein expression were obtained 2-12 h after capsaicin enemas. Capsaicin 116-125 transforming growth factor alpha Rattus norvegicus 21-29 11989832-10 2002 A 2-fold increase of TGFalpha mRNA and a 10-fold increase of TGFalpha protein expression were obtained 2-12 h after capsaicin enemas. Capsaicin 116-125 transforming growth factor alpha Rattus norvegicus 61-69 11989832-12 2002 CONCLUSION: Capsaicin-sensitive nerve fibres modulate epithelial cell proliferation and TGFalpha expression in colonic mucosa as well as a migration of inflammatory cells into the colonic mucosa. Capsaicin 12-21 transforming growth factor alpha Rattus norvegicus 88-96