PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25088915-4 2014 We found that CB1, NGF receptor tyrosine kinase A (trkA), and TRPV1 are present in cultured adult mouse small- to medium-sized afferent neurons and treatment with NGF (100ng/ml) for 30 min significantly increased the number of neurons that responded to capsaicin (as indicated by increased intracellular Ca(2 +) concentration). Capsaicin 253-262 nerve growth factor Mus musculus 19-22 6182949-4 1982 Supplementation of guinea pigs with mouse NGF completely prevented capsaicin-induced substance P depletion. Capsaicin 67-76 nerve growth factor Mus musculus 42-45 30260982-10 2018 When neurites of NGF cultured somata were grown in GDNF, capsaicin evoked a lower CGRP release than high potassium, compared to those grown in NGF. Capsaicin 57-66 nerve growth factor Mus musculus 17-20 25088915-4 2014 We found that CB1, NGF receptor tyrosine kinase A (trkA), and TRPV1 are present in cultured adult mouse small- to medium-sized afferent neurons and treatment with NGF (100ng/ml) for 30 min significantly increased the number of neurons that responded to capsaicin (as indicated by increased intracellular Ca(2 +) concentration). Capsaicin 253-262 nerve growth factor Mus musculus 163-166 25088915-7 2014 Blocking PI3 kinase activity also attenuated the NGF-induced increase in the number of neurons that responded to capsaicin. Capsaicin 113-122 nerve growth factor Mus musculus 49-52 12231491-8 2002 Furthermore, CCSP-NGF-tg mice developed an increased reactivity of sensory neurons in response to inhaled capsaicin demonstrating NGF-mediated neuronal plasticity. Capsaicin 106-115 nerve growth factor Mus musculus 18-21 16914685-1 2006 Nerve growth factor (NGF) has been implicated as an effector of inflammatory pain because it sensitizes primary afferents to noxious thermal, mechanical, and chemical [e.g., capsaicin, a transient receptor potential vanilloid receptor 1 (TRPV1) agonist] stimuli and because NGF levels increase during inflammation. Capsaicin 174-183 nerve growth factor Mus musculus 0-19 16914685-1 2006 Nerve growth factor (NGF) has been implicated as an effector of inflammatory pain because it sensitizes primary afferents to noxious thermal, mechanical, and chemical [e.g., capsaicin, a transient receptor potential vanilloid receptor 1 (TRPV1) agonist] stimuli and because NGF levels increase during inflammation. Capsaicin 174-183 nerve growth factor Mus musculus 21-24 16914685-1 2006 Nerve growth factor (NGF) has been implicated as an effector of inflammatory pain because it sensitizes primary afferents to noxious thermal, mechanical, and chemical [e.g., capsaicin, a transient receptor potential vanilloid receptor 1 (TRPV1) agonist] stimuli and because NGF levels increase during inflammation. Capsaicin 174-183 nerve growth factor Mus musculus 274-277 16777323-4 2006 Treatment of rats with NGF over a 13-day period produced a significant increase in capsaicin-evoked iCGRP release from isolated biopsies of hindpaw skin, as assessed by in vitro superfusion and RIA. Capsaicin 83-92 nerve growth factor Mus musculus 23-26 16777323-6 2006 This NGF enhancement of capsaicin-evoked iCGRP release was not due solely to increases in peripheral iCGRP content since only the 1mg/kg dose of NGF elevated cutaneous pools of iCGRP, whereas both doses significantly increased capsaicin-evoked peptide release. Capsaicin 24-33 nerve growth factor Mus musculus 5-8 16777323-6 2006 This NGF enhancement of capsaicin-evoked iCGRP release was not due solely to increases in peripheral iCGRP content since only the 1mg/kg dose of NGF elevated cutaneous pools of iCGRP, whereas both doses significantly increased capsaicin-evoked peptide release. Capsaicin 24-33 nerve growth factor Mus musculus 145-148 16777323-6 2006 This NGF enhancement of capsaicin-evoked iCGRP release was not due solely to increases in peripheral iCGRP content since only the 1mg/kg dose of NGF elevated cutaneous pools of iCGRP, whereas both doses significantly increased capsaicin-evoked peptide release. Capsaicin 227-236 nerve growth factor Mus musculus 5-8 16777323-7 2006 Moreover, NGF also enhanced capsaicin-evoked thermal hyperalgesia under similar dose- and time-related conditions. Capsaicin 28-37 nerve growth factor Mus musculus 10-13 16777323-8 2006 Collectively, the chronic administration of NGF not only increases capsaicin-evoked hyperalgesia, but also significantly primes peripheral fibers to enhanced peptidergic exocytosis following activation of the capsaicin receptor. Capsaicin 67-76 nerve growth factor Mus musculus 44-47 12231491-8 2002 Furthermore, CCSP-NGF-tg mice developed an increased reactivity of sensory neurons in response to inhaled capsaicin demonstrating NGF-mediated neuronal plasticity. Capsaicin 106-115 nerve growth factor Mus musculus 130-133 11710915-7 2001 Additional studies also demonstrated a significant in vivo upregulation of keratinocyte nerve growth factor expression in murine epidermis after the topical application of the neuropeptide releasing agent capsaicin. Capsaicin 205-214 nerve growth factor Mus musculus 88-107 10976461-0 2000 [The effect of anti-NGF and NGF on the responses to noxious heat in mice treated with capsaicin in the neonatal period]. Capsaicin 86-95 nerve growth factor Mus musculus 15-31 10976461-7 2000 Withdrawal latencies of the mice treated with both capsaicin and anti-NGF were significantly retarded compared with those of the animals treated with only capsaicin. Capsaicin 155-164 nerve growth factor Mus musculus 70-73 10976461-9 2000 On the other hand, the latencies of the mice treated with both capsaicin and NGF were short compared with those of the animals treated with only capsaicin. Capsaicin 145-154 nerve growth factor Mus musculus 77-80 9476901-7 1998 CCSP-NGF mice were more sensitive than normal mice to capsaicin-induced increases in respiratory system resistance, demonstrating that the increased sensory innervation led to a change in airway function. Capsaicin 54-63 nerve growth factor Mus musculus 5-8 7697868-7 1994 The development of capsaicin sensitivity in neural crest cultures was dependent on time in culture and on the presence of NGF. Capsaicin 19-28 nerve growth factor Mus musculus 122-125 33806699-0 2021 Ca2+ Signalling Induced by NGF Identifies a Subset of Capsaicin-Excitable Neurons Displaying Enhanced Chemo-Nociception in Dorsal Root Ganglion Explants from Adult pirt-GCaMP3 Mouse. Capsaicin 54-63 nerve growth factor Mus musculus 27-30 33806699-2 2021 Nerve growth factor (NGF) sensitises TRPV1 to capsaicin (CAPS), modulates nociceptor excitability and induces thermal hyperalgesia, but cellular mechanisms remain unclear. Capsaicin 46-55 nerve growth factor Mus musculus 0-19 33806699-2 2021 Nerve growth factor (NGF) sensitises TRPV1 to capsaicin (CAPS), modulates nociceptor excitability and induces thermal hyperalgesia, but cellular mechanisms remain unclear. Capsaicin 46-55 nerve growth factor Mus musculus 21-24 33806699-2 2021 Nerve growth factor (NGF) sensitises TRPV1 to capsaicin (CAPS), modulates nociceptor excitability and induces thermal hyperalgesia, but cellular mechanisms remain unclear. Capsaicin 57-61 nerve growth factor Mus musculus 0-19 33806699-2 2021 Nerve growth factor (NGF) sensitises TRPV1 to capsaicin (CAPS), modulates nociceptor excitability and induces thermal hyperalgesia, but cellular mechanisms remain unclear. Capsaicin 57-61 nerve growth factor Mus musculus 21-24