PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21708955-14 2011 Repeated excitation and capsaicin also restored contractility, possibly because of the release of endogenous CGRP from nerve endings in the isolated muscles. Capsaicin 24-33 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 109-113 21741970-0 2011 Characterization of capsaicin induced responses in mice vas deferens: evidence of CGRP uptake. Capsaicin 20-29 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 82-86 21741970-2 2011 Capsaicin can stimulate the release of CGRP from intracellular stores of these nerves, but this phenomenon has not been investigated in-depth in isolated preparations. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 39-43 21741970-8 2011 The addition of CGRP receptor antagonists caused a transient potentiation of the twitch response and this potentiation was blocked by pretreatment with capsaicin and enhanced by incubation with exogenous CGRP. Capsaicin 152-161 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 16-20 21741970-9 2011 During the second consecutive cumulative concentration-response curve with capsaicin, the first phase of concentration-response curve disappeared and this was partially restored when the mouse vas deferens was preincubated with CGRP, suggesting the uptake of exogenous CGRP by nerves. Capsaicin 75-84 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 228-232 21741970-9 2011 During the second consecutive cumulative concentration-response curve with capsaicin, the first phase of concentration-response curve disappeared and this was partially restored when the mouse vas deferens was preincubated with CGRP, suggesting the uptake of exogenous CGRP by nerves. Capsaicin 75-84 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 269-273 21741970-10 2011 Besides showing capsaicin-induced CGRP releases this study shows that exogenous CGRP can be taken up in vas deferens and can be re-released. Capsaicin 16-25 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 34-38 21741970-10 2011 Besides showing capsaicin-induced CGRP releases this study shows that exogenous CGRP can be taken up in vas deferens and can be re-released. Capsaicin 16-25 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 80-84 21525372-5 2011 Our results demonstrate that SynGAP is expressed in primary afferent sensory neurons and that the capsaicin-stimulated CGRP release from spinal cord slices was two-fold higher from SynGAP(+/-) mice than that observed from WT mouse tissue, consistent with an increase in expression of the capsaicin receptor, transient receptor potential cation channel subfamily V member 1 (TRPV1), in SynGAP(+/-) dorsal root ganglia. Capsaicin 98-107 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 119-123 21514666-4 2011 Isolated rat and mouse skin preparations were used to measure CGRP release induced by noxious heat (47 C) and capsaicin (0.5muM), stimuli known to activate the capsaicin receptor TRPV1. Capsaicin 110-119 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 62-66 19285119-0 2009 Glial cell line-derived neurotrophic factor family ligands enhance capsaicin-stimulated release of calcitonin gene-related peptide from sensory neurons. Capsaicin 67-76 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 99-130 19878665-6 2010 Capsaicin and SA13353 increased serum neuropeptide levels, and calcitonin gene-related peptide fragment 8-37 (CGRP(8)(-)(37)), a CGRP antagonist, partially blocked the inhibitory effects of capsaicin and SA13353 on LPS-induced TNF-alpha production. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 129-133 19878665-6 2010 Capsaicin and SA13353 increased serum neuropeptide levels, and calcitonin gene-related peptide fragment 8-37 (CGRP(8)(-)(37)), a CGRP antagonist, partially blocked the inhibitory effects of capsaicin and SA13353 on LPS-induced TNF-alpha production. Capsaicin 190-199 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 110-114 19595440-4 2009 Significant increases of the hippocampal tissue levels of CGRP, IGF-I, and IGF-I messenger RNA (mRNA) were observed after capsaicin administration in WT mice (P < 0.01) but not in CGRP-/- mice. Capsaicin 122-131 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 58-62 19595440-4 2009 Significant increases of the hippocampal tissue levels of CGRP, IGF-I, and IGF-I messenger RNA (mRNA) were observed after capsaicin administration in WT mice (P < 0.01) but not in CGRP-/- mice. Capsaicin 122-131 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 183-187 19595440-8 2009 Capsaicin-induced improvement of the spatial learning was reversed by administration of an anti-IGF-I antibody and by that of a CGRP receptor antagonist CGRP (8-37) in WT mice. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 128-132 19595440-8 2009 Capsaicin-induced improvement of the spatial learning was reversed by administration of an anti-IGF-I antibody and by that of a CGRP receptor antagonist CGRP (8-37) in WT mice. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 153-157 19595440-10 2009 These observations strongly suggest that the stimulation of sensory neurons by capsaicin might increase IGF-I production via increasing the hippocampal tissue CGRP levels, and it may thereby promote angiogenesis and neurogenesis to produce improvement of the cognitive function in mice. Capsaicin 79-88 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 159-163 19285119-3 2009 Exposure of isolated sensory neurons in culture to GDNF, neurturin, and artemin enhanced the capsaicin-stimulated release of immunoreactive calcitonin gene-related peptide (iCGRP) two- to threefold, but did not increase potassium-stimulated release of iCGRP. Capsaicin 93-102 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 140-171 19860701-4 2009 CGRP is considered a marker of afferent fibers in the upper gastrointestinal tract being almost completely depleted following treatment with the selective neurotoxin capsaicin that targets these fibers via transient receptor potential vanilloid of type-1. Capsaicin 166-175 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 0-4 18423881-8 2008 Selective elimination of unmyelinated C-fibers by neonatal capsaicin treatment resulted in marked reduction of the c-kit receptor and CGRP expression in the superficial layer of the spinal cord. Capsaicin 59-68 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 134-138 18789524-2 2008 Capsaicin causes neurons in the dorsal root ganglia (DRG) to release CGRP from their central and/or peripheral axons, suggesting a functional link between CGRP and the capsaicin receptor TRPV1. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 69-73 18789524-2 2008 Capsaicin causes neurons in the dorsal root ganglia (DRG) to release CGRP from their central and/or peripheral axons, suggesting a functional link between CGRP and the capsaicin receptor TRPV1. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 155-159 18987195-4 2008 Capsaicin-evoked CGRP release from spinal cord tissue and capsaicin-evoked action potentials on isolated skin-nerve preparation were significantly decreased in CB(1)KO mice. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 17-21 18958364-6 2008 Measuring the levels of SP and CGRP by radioimmunoassay, we demonstrated that capsaicin-stimulated release of neuropeptides is 3-5 folds higher in spinal cord slices from Nf1+/- mice than that from wildtype mouse tissue. Capsaicin 78-87 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 31-35 18958364-7 2008 In addition, the potassium- and capsaicin-stimulated release of CGRP from the culture of sensory neurons isolated from Nf1+/- mice was more than double that from the culture of wildtype neurons. Capsaicin 32-41 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 64-68 18344596-0 2008 The effect of neonatal capsaicin treatment on the CGRP-immunoreaction in the trigeminal subnucleus caudalis of mice. Capsaicin 23-32 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 50-54 18192222-1 2008 Calcitonin gene-related peptide (CGRP), a potent vasodilator released from capsaicin-sensitive C-fiber and Adelta-fiber sensory nerves, has been suggested to play a beneficial role in myocardial ischemia-reperfusion (I/R) injury. Capsaicin 75-84 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 33-37 19075656-3 2008 Stimulation of sensory neurons by capsaicin increases tissue levels of IGF-I and IGF-I mRNA in various organs via increased calcitonin gene-related peptide (CGRP) release in mice. Capsaicin 34-43 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 124-155 19075656-3 2008 Stimulation of sensory neurons by capsaicin increases tissue levels of IGF-I and IGF-I mRNA in various organs via increased calcitonin gene-related peptide (CGRP) release in mice. Capsaicin 34-43 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 157-161 19075656-9 2008 Administration of capsaicin increases CGRP and IGF-I levels in plasma, kidneys and the heart in SHR to WKY levels, and normalizes mean arterial blood pressure in SHR. Capsaicin 18-27 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 38-42 17291600-1 2007 Substance P (SP) and calcitonin gene-related peptide (CGRP) released from capsaicin-sensitive afferents induce neurogenic inflammation via NK(1), NK(2) and CGRP1 receptor activation. Capsaicin 74-83 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 21-52 17906682-1 2007 BACKGROUND AND PURPOSE: Calcitonin gene-related peptide (CGRP), a capsaicin-sensitive neuromodulator of splanchnic vascular tone in several animal species, remains poorly investigated in mouse models. Capsaicin 66-75 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 24-55 17906682-1 2007 BACKGROUND AND PURPOSE: Calcitonin gene-related peptide (CGRP), a capsaicin-sensitive neuromodulator of splanchnic vascular tone in several animal species, remains poorly investigated in mouse models. Capsaicin 66-75 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 57-61 17569567-2 2007 Capsaicin activates vanilloid receptor-1, thereby increasing the release of calcitonin gene-related peptide (CGRP) from sensory neurons, and CGRP has been shown to increase IGF-I production. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 76-107 17569567-2 2007 Capsaicin activates vanilloid receptor-1, thereby increasing the release of calcitonin gene-related peptide (CGRP) from sensory neurons, and CGRP has been shown to increase IGF-I production. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 109-113 18054007-7 2008 Fifty percent ethanol containing capsaicin immediately increased intragastric levels of CGRP in wild-type (WT) mice, although 50% ethanol alone did not. Capsaicin 33-42 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 88-92 18054007-8 2008 The protective action of capsaicin against ethanol was completely abolished in CGRP(-/-). Capsaicin 25-34 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 79-83 17291600-1 2007 Substance P (SP) and calcitonin gene-related peptide (CGRP) released from capsaicin-sensitive afferents induce neurogenic inflammation via NK(1), NK(2) and CGRP1 receptor activation. Capsaicin 74-83 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 54-58 17291600-1 2007 Substance P (SP) and calcitonin gene-related peptide (CGRP) released from capsaicin-sensitive afferents induce neurogenic inflammation via NK(1), NK(2) and CGRP1 receptor activation. Capsaicin 74-83 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 156-161 16413055-9 2006 Capsaicin, bradykinin and the potassium solution caused concentration-dependent increases in CGRP release. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 93-97 17525595-6 2007 Selective knockdown of CGRP in primary afferents significantly attenuated the thermal, C-fiber hyperalgesia normally observed after topical application of capsaicin. Capsaicin 155-164 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 23-27 17360009-9 2007 These observations suggested that capsaicin-induced sensory neuron activation, which leads to release of CGRP, might increase IGF-I production, thereby reducing reperfusion-induced liver injury by reducing apoptosis. Capsaicin 34-43 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 105-109 17307377-1 2007 Capsaicin increases calcitonin gene-related peptide (CGRP) release from sensory neurons by stimulating vanilloid receptor-1 (VR-1). Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 20-51 17307377-1 2007 Capsaicin increases calcitonin gene-related peptide (CGRP) release from sensory neurons by stimulating vanilloid receptor-1 (VR-1). Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 53-57 17307377-2 2007 Since CGRP increases production of insulin-like growth factor-I (IGF-I) in fetal osteoblasts in vitro, it is possible that sensory neuron activation by capsaicin increases production of IGF-I. Capsaicin 152-161 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 6-10 12768286-3 2003 Neurochemical characterization of extrinsic primary afferent neurons (EPANs) in normal and capsaicin-treated mice, revealed that CGRP and VR1, but not SP, were expressed in extrinsic afferents. Capsaicin 91-100 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 129-133 16553616-14 2006 Experiments on capsaicin-induced CGRP release in tissue from CB1-/- mice ruled out a CB1-mediated effect. Capsaicin 15-24 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 33-37 16143644-7 2006 Administration of exogenous CGRP or induction of endogenous CGRP release by treatment with capsaicin 24 h before I/R mimicked the postischemic anti-inflammatory effects of antecedent ethanol ingestion. Capsaicin 91-100 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 60-64 16143644-8 2006 Preconditioning with capsaicin 24 h before I/R was prevented by coincident treatment with CGRP-(8-37), while exogenous CGRP induced an anti-inflammatory phenotype in mice depleted of CGRP by capsaicin administration 4 days earlier. Capsaicin 21-30 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 90-94 16143644-8 2006 Preconditioning with capsaicin 24 h before I/R was prevented by coincident treatment with CGRP-(8-37), while exogenous CGRP induced an anti-inflammatory phenotype in mice depleted of CGRP by capsaicin administration 4 days earlier. Capsaicin 191-200 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 119-123 16143644-8 2006 Preconditioning with capsaicin 24 h before I/R was prevented by coincident treatment with CGRP-(8-37), while exogenous CGRP induced an anti-inflammatory phenotype in mice depleted of CGRP by capsaicin administration 4 days earlier. Capsaicin 191-200 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 119-123 16918352-1 2006 Capsaicin-sensitive sensory neurons are nociceptive neurons that release calcitonin gene-related peptide (CGRP) on activation. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 73-104 16918352-1 2006 Capsaicin-sensitive sensory neurons are nociceptive neurons that release calcitonin gene-related peptide (CGRP) on activation. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 106-110 12912853-2 2003 Administration of capsaicin also inhibited ethanol induced gastric mucosal injury through immediate release of CGRP from primary sensory neurones, which is termed the neural emergency system. Capsaicin 18-27 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 111-115 12912853-9 2003 Fifty per cent ethanol containing capsaicin (480 micro M) immediately increased intragastric levels of CGRP although 50% ethanol alone did not. Capsaicin 34-43 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 103-107 12912853-10 2003 The protective action of capsaicin (480 micro M) against ethanol was completely abolished by intravenous injection of CGRP-(8-37). Capsaicin 25-34 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 118-122 12912853-11 2003 Indomethacin also inhibited the protective action of capsaicin, and this was accompanied by reduced levels of intragastric CGRP. Capsaicin 53-62 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 123-127 12912853-17 2003 CONCLUSIONS: The present results suggest that endogenous prostaglandin I(2) enhances the protective action of the capsaicin mediated neural emergency system against ethanol induced gastric mucosal injury through enhancement of CGRP release. Capsaicin 114-123 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 227-231 15639479-9 2005 Capsaicin caused massive CGRP release in all mouse genotypes with the exception of TRPV1-/-. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 25-29 15183508-2 2004 In this study we demonstrate that similar functions, including capsaicin-induced CGRP release, are to be found in the desheathed sciatic nerve of the mouse. Capsaicin 63-72 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 81-85 15183508-7 2004 After capsaicin stimulation (10(-6) M for 5 min), the fibers appeared depleted of CGRP with only few vesicles remaining as well as some residual staining of the axoplasm. Capsaicin 6-15 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 82-86 11514080-5 2001 Capsaicin, heat and pH 5.2 were able to induce significant increases in calcitonin gene related peptide (CGRP) release (14.6-, 5.1-, and 2.3-fold over baseline), however, only capsaicin induced a significant increase in substance P (SP) levels (1.8-fold over baseline). Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 72-103 11858952-6 2002 Intradermal injections of capsaicin prior to UVB-irradiation inhibited the UVB-induced CGRP expression, BrdU labeling in basal keratinocytes and epidermal thickening. Capsaicin 26-35 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 87-91 11815370-7 2002 The CGRP receptor antagonist CGRP(8 - 37) (400 nmol kg(-1)) had no effect on capsaicin-induced blood flow in NK(1)+/+mice but abolished the increased blood flow to capsaicin in NK(1)-/-, and NK(1)+/+wild-type mice pre-treated with SR140333. Capsaicin 164-173 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 4-8 11815370-7 2002 The CGRP receptor antagonist CGRP(8 - 37) (400 nmol kg(-1)) had no effect on capsaicin-induced blood flow in NK(1)+/+mice but abolished the increased blood flow to capsaicin in NK(1)-/-, and NK(1)+/+wild-type mice pre-treated with SR140333. Capsaicin 164-173 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 29-33 11815370-9 2002 The capsaicin-induced increased blood flow involves activation of, and possible interactions between, both NK(1) and CGRP(1) receptors. Capsaicin 4-13 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 117-121 11514080-5 2001 Capsaicin, heat and pH 5.2 were able to induce significant increases in calcitonin gene related peptide (CGRP) release (14.6-, 5.1-, and 2.3-fold over baseline), however, only capsaicin induced a significant increase in substance P (SP) levels (1.8-fold over baseline). Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 105-109 7955356-3 1994 Treatment of cultures with the capsaicin analog resiniferatoxin (RTX; 0.3-30 nM) significantly augmented CGRP immunoreactivity per neuron at all ages investigated without increasing the number of CGRP-immunoreactive cells. Capsaicin 31-40 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 105-109 1378463-9 1992 It is concluded that the mouse pancreas contains capsaicin-sensitive sensory CGRP- and substance P-immunoreactive nerve fibers, whereas the galanin-immunoreactive nerve fibers are not sensitive to capsaicin. Capsaicin 49-58 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 77-81 8107527-4 1994 Moreover, pretreatment with capsaicin is able to mimic the anti-inflammatory effect of exogenous CGRP, while simultaneous administration of CGRP and capsaicin produces a reduced response. Capsaicin 28-37 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 97-101 33849430-7 2021 RESULTS: Pre-incubation with either petasin or isopetasin reduced mustard oil- and capsaicin-evoked CGRP release compared to vehicle in an approximately dose-dependent manner. Capsaicin 83-92 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 100-104 34249519-1 2021 Background: The calcitonin gene-related peptide (CGRP) is a neuropeptide that is released from capsaicin-sensitive nerves as a potent vasodilator involved in nociceptive transmission. Capsaicin 95-104 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 16-47 34249519-1 2021 Background: The calcitonin gene-related peptide (CGRP) is a neuropeptide that is released from capsaicin-sensitive nerves as a potent vasodilator involved in nociceptive transmission. Capsaicin 95-104 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 49-53 35183536-9 2022 A prolonged pre-exposure to capsaicin or BIBN4096 (1 muM), a CGRP receptor antagonist, inhibited the mechanostimulation-induced reduction in the SPC frequency, but did not block the increase in SPC amplitude. Capsaicin 28-37 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 61-65 32640973-0 2020 Neuropeptide FF receptor 2 inhibits capsaicin-induced CGRP Upregulation in mouse trigeminal ganglion. Capsaicin 36-45 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 54-58 33287697-0 2020 Correction to: The knockdown of Neuropeptide FF receptor 2 inhibits capsaicin-induced CGRP Upregulation in mouse trigeminal ganglion. Capsaicin 68-77 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 86-90 32640973-7 2020 Mice pretreated with Npffr2-shRNA or NPFFR2 knockouts were adopted to test the impact of NPFFR2 on capsaicin-induced CGRP upregulation in trigeminal ganglion. Capsaicin 99-108 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 117-121 32640973-11 2020 FINDINGS: Infusion of capsaicin into the cisterna magna upregulated the CGRP in trigeminal ganglion and induced spontaneous pain behaviors including the reduction of locomotor activity and the increase of freezing behavior. Capsaicin 22-31 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 72-76 32640973-13 2020 Mice pretreatment with Npffr2-shRNA prevented capsaicin-induced CGRP upregulation in trigeminal ganglion. Capsaicin 46-55 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 64-68 32640973-16 2020 CONCLUSIONS: Reducing the level of NPFFR2 leads to the downregulation of capsaicin-induced CGRP in trigeminal ganglion, which would consequently attenuate the activation of trigeminovascular pathway. Capsaicin 73-82 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 91-95 29732591-7 2018 Similarly, both capsaicin and a depolarizing solution of 60 mM KCl evoked CGRP release in saphenous but not vagus nerves. Capsaicin 16-25 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 74-78 31194993-8 2019 The results also showed that TRPV1 agonist, Capsaicin boosted the SIRT6-induced glucose uptake, CGRP production, and GLUT4 levels. Capsaicin 44-53 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 96-100 30260982-10 2018 When neurites of NGF cultured somata were grown in GDNF, capsaicin evoked a lower CGRP release than high potassium, compared to those grown in NGF. Capsaicin 57-66 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 82-86 30830967-11 2019 In the DRG, MaR1 reduced CFA-induced Nav1.8 and Trpv1 mRNA expression and calcium influx and capsaicin-induced release of CGRP by DRG neurons. Capsaicin 93-102 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 122-126 27525636-11 2016 H2S activates capsaicin-sensitive sensory nerves through TRPA1 receptors and the resultant vasodilatation is mediated by the release of vasoactive sensory neuropeptides CGRP and substance P. Capsaicin 14-23 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 169-173 29328505-1 2018 BACKGROUND AND PURPOSE: Capsaicin-mediated modulation of taste nerve responses is thought to be produced indirectly by the actions of neuropeptides, for example, CGRP and substance P (SP), on taste cells implying they play a role in taste sensitivity. Capsaicin 24-33 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 162-166 29991229-8 2018 Meanwhile, phenylephrine-induced relaxation was inhibited by pretreatment with propranolol and calcitonin gene-related peptide (CGRP)-depletory capsaicin in UB strips with and without mucosa. Capsaicin 144-153 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 95-126 29991229-8 2018 Meanwhile, phenylephrine-induced relaxation was inhibited by pretreatment with propranolol and calcitonin gene-related peptide (CGRP)-depletory capsaicin in UB strips with and without mucosa. Capsaicin 144-153 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 128-132 29478714-7 2018 Sensory deafferentation evoked by pretreatment with high doses of capsaicin markedly exacerbated DSS-induced colitis with reductions in DSS-induced upregulation of SP- and CGRP-positive nerve fibers. Capsaicin 66-75 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 172-176 29247491-4 2018 We found that the lipophilic capsaicin, mustard oil and menthol effectively get access to the nerve endings below the multilayered squamous epithelium, while cigarette smoke and its gaseous phase were weakly effective releasing CGRP. Capsaicin 29-38 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 228-232 25297108-6 2014 Functionally, endogenous GDNF released from peptidergic CGRP/somatostatin+ nociceptors upon capsaicin stimulation exert a tonic inhibitory control on the glutamate excitatory drive of SDH neurons as measured after ERK1/2 phosphorylation assay. Capsaicin 92-101 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 56-60 26914965-7 2016 Capsaicin-induced and to a lesser extent also KCl-induced CGRP releases were also augmented after Bv8 treatment. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 58-62 24506953-7 2014 Capsaicin stimulation of TRPV1 provoked concentration-dependent CGRP release. Capsaicin 0-9 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 64-68 22080974-4 2012 TRPV1 activation by capsaicin and acidic solution (pH 5.1) induced colonic CGRP/SP release, measured by EIA. Capsaicin 20-29 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 75-79 22721614-1 2012 Activation of transient receptor potential ankyrin 1 (TRPA1) and vanilloid 1 (TRPV1) channels on capsaicin-sensitive sensory neurons causes release of inflammatory neuropeptides, including calcitonin gene-related peptide (CGRP). Capsaicin 97-106 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 189-220 22721614-1 2012 Activation of transient receptor potential ankyrin 1 (TRPA1) and vanilloid 1 (TRPV1) channels on capsaicin-sensitive sensory neurons causes release of inflammatory neuropeptides, including calcitonin gene-related peptide (CGRP). Capsaicin 97-106 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 222-226 23123709-4 2012 Studies showing that CGRP physiologically regulates skin inflammation using a CGRP antagonist, capsaicin-induced depletion model, RAMP1-deficient mice and mouse contact hypersensitivity (CHS) model have been reported. Capsaicin 95-104 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 21-25