PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28671132-3 2017 Capsaicin, a specific agonist of the transient receptor potential vanilloid 1 (TRPV1), has been proven to ameliorate stress-induced AD-like pathological and cognitive impairments, but it is unclear whether TRPV1 activation can affect cognitive and synaptic functions in Abeta-induced mouse model of AD. Capsaicin 0-9 amyloid beta (A4) precursor protein Mus musculus 270-275 32661266-5 2020 In the present study, we found that intake of capsaicin, the pungent ingredient in chili peppers, reduced brain Abeta burden and rescued cognitive decline in APP/PS1 mice. Capsaicin 46-55 amyloid beta (A4) precursor protein Mus musculus 112-117 32661266-6 2020 Our in vivo and in vitro studies revealed that capsaicin shifted Amyloid precursor protein (APP) processing towards alpha-cleavage and precluded Abeta generation by promoting the maturation of a disintegrin and metalloproteinase 10 (ADAM10). Capsaicin 47-56 amyloid beta (A4) precursor protein Mus musculus 65-90 32661266-6 2020 Our in vivo and in vitro studies revealed that capsaicin shifted Amyloid precursor protein (APP) processing towards alpha-cleavage and precluded Abeta generation by promoting the maturation of a disintegrin and metalloproteinase 10 (ADAM10). Capsaicin 47-56 amyloid beta (A4) precursor protein Mus musculus 145-150