PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32992584-11 2020 Our findings demonstrate a key role for plasma gelsolin in erythropoiesis and in gelsolin-depleted MDS patients, and raises the possibility that pGSN administration may promote erythropoiesis in erythroid dysplasia. pgsn 145-149 gelsolin Homo sapiens 47-55 17135294-1 2007 Gelsolin is a highly conserved intracellular actin-binding protein with an extracellular isoform, plasma gelsolin (pGSN). pgsn 115-119 gelsolin Homo sapiens 0-8 17135294-1 2007 Gelsolin is a highly conserved intracellular actin-binding protein with an extracellular isoform, plasma gelsolin (pGSN). pgsn 115-119 gelsolin Homo sapiens 105-113 26439960-4 2015 Recombinant human pGSN (rhp-GSN) decreased extracellular actin and myeloperoxidase activity in the brain, resulting in reduced disease activity and less severe clinical disease, suggesting that gelsolin could be a potential therapeutic target for MS. pgsn 18-22 gelsolin Homo sapiens 194-202 30711007-1 2019 BACKGROUND: Human plasma gelsolin (pGSN) is a multifunctional actin-binding protein involved in a variety of biological processes, including neutralization of pro-inflammatory molecules such as lipopolysaccharide (LPS) and lipoteichoic acid (LTA) and modulation of host inflammatory response. pgsn 35-39 gelsolin Homo sapiens 25-33 30511541-5 2018 In this study, the aim was to determine the clinical predictiveness of plasma gelsolin levels (pGSN) in acute bronchiolitis. pgsn 95-99 gelsolin Homo sapiens 78-86 26318415-3 2016 OBJECTIVE: We aimed to determine plasma gelsolin (pGSN) levels in children with atopic dermatitis (AD). pgsn 50-54 gelsolin Homo sapiens 40-48 27939478-3 2016 We hypothesized that syncytiotrophoblast extracellular vesicles exposes cytoplasmic actin to plasma resulting in depletion of plasma gelsolin (pGSN), an abundant plasma protein that scavenges circulating actin and other pro-inflammatory mediators. pgsn 143-147 gelsolin Homo sapiens 133-141 26902273-1 2016 OBJECTIVE: To investigate the changes in plasma gelsolin (pGSN) levels in severe burn patients with sepsis, and to evaluate the prognosis of patients when combined with other related clinical indexes. pgsn 58-62 gelsolin Homo sapiens 48-56 24393331-2 2014 In particular, plasma-type gelsolin (pGSN) can ameliorate deleterious inflammatory response by scavenging pro-inflammatory signals such as actin and lipopolysaccharide. pgsn 37-41 gelsolin Homo sapiens 27-35 22082609-7 2012 Upon establishing the accurate levels of pGSN in healthy individuals, this biomarker would predict the prognosis/disease progression in multiple health conditions and help in prioritizing the ones in-need of gelsolin replacement therapy. pgsn 41-45 gelsolin Homo sapiens 208-216 25126004-3 2014 The purpose of this study was to investigate the perioperative changes of plasma gelsolin (pGSN) in patients below 3 years of age with cardiac surgeries and CPB, and determine whether pGSN are associated with the occurrence and severity of CPB-ALI. pgsn 91-95 gelsolin Homo sapiens 81-89 23985203-1 2013 OBJECTIVE: To observe the changes in plasma gelsolin (pGSN) level of patients with severe burn and to explore its relationship with sepsis and death of patients. pgsn 54-58 gelsolin Homo sapiens 44-52