PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23802426-0	2013	Design, synthesis, and biological evaluation of acetophenone derivatives as dual binding acetylcholinesterase inhibitors.	acetophenone	48-60	acetylcholinesterase (Cartwright blood group)	Homo sapiens	89-109	
2709330-7	1989	Therefore, the phenyl substitution appears to increase greatly the selectivity of the compound for AChE.	acetophenone	15-21	acetylcholinesterase (Cartwright blood group)	Homo sapiens	99-103	
33260981-1	2020	Kinetic studies and molecular modeling of human acetylcholinesterase (AChE) inhibition by a fluorinated acetophenone derivative, 1-(3-tert-butylphenyl)-2,2,2-trifluoroethanone (TFK), were performed.	acetophenone	104-116	acetylcholinesterase (Cartwright blood group)	Homo sapiens	48-68	
33260981-1	2020	Kinetic studies and molecular modeling of human acetylcholinesterase (AChE) inhibition by a fluorinated acetophenone derivative, 1-(3-tert-butylphenyl)-2,2,2-trifluoroethanone (TFK), were performed.	acetophenone	104-116	acetylcholinesterase (Cartwright blood group)	Homo sapiens	70-74	
27637382-3	2016	Various fluorinated acetophenone derivatives bind to acetylcholinesterase with high affinity, including 2,2,2-trifluoro-1-(3-dimethylaminophenyl)ethanone (1) and 1-(3-tert-butylphenyl)-2,2,2-trifluoroethanone (2).	acetophenone	20-32	acetylcholinesterase (Cartwright blood group)	Homo sapiens	53-73	
23802426-1	2013	As part of a project aimed at developing new agents for potential application in Alzheimer"s disease, a new series of acetophenone derivatives which possess alkylamine side chains were designed, synthesized and assayed as acetylcholinesterase (AChE) inhibitors that could simultaneously bind to the peripheral and catalytic sites of the enzyme.	acetophenone	118-130	acetylcholinesterase (Cartwright blood group)	Homo sapiens	222-242	
23802426-1	2013	As part of a project aimed at developing new agents for potential application in Alzheimer"s disease, a new series of acetophenone derivatives which possess alkylamine side chains were designed, synthesized and assayed as acetylcholinesterase (AChE) inhibitors that could simultaneously bind to the peripheral and catalytic sites of the enzyme.	acetophenone	118-130	acetylcholinesterase (Cartwright blood group)	Homo sapiens	244-248