PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16537646-0	2006	CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes.	Triglycerides	62-74	cAMP responsive element binding protein 1	Mus musculus	0-4	
29127035-8	2018	Finally, inhibition of cAMP responsive element binding protein (CREB), a PPARgamma coactivator, partially mitigated pyraclostrobin-induced TG accumulation, suggesting TG accumulation is occurring through a CREB-driven mechanism.	Triglycerides	139-141	cAMP responsive element binding protein 1	Mus musculus	23-62	
29127035-8	2018	Finally, inhibition of cAMP responsive element binding protein (CREB), a PPARgamma coactivator, partially mitigated pyraclostrobin-induced TG accumulation, suggesting TG accumulation is occurring through a CREB-driven mechanism.	Triglycerides	139-141	cAMP responsive element binding protein 1	Mus musculus	64-68	
29127035-8	2018	Finally, inhibition of cAMP responsive element binding protein (CREB), a PPARgamma coactivator, partially mitigated pyraclostrobin-induced TG accumulation, suggesting TG accumulation is occurring through a CREB-driven mechanism.	Triglycerides	167-169	cAMP responsive element binding protein 1	Mus musculus	23-62	
29127035-8	2018	Finally, inhibition of cAMP responsive element binding protein (CREB), a PPARgamma coactivator, partially mitigated pyraclostrobin-induced TG accumulation, suggesting TG accumulation is occurring through a CREB-driven mechanism.	Triglycerides	167-169	cAMP responsive element binding protein 1	Mus musculus	64-68	
16537646-8	2006	We also demonstrate that overexpression of two dominant negative mutants of the cAMP-response element-binding protein CREB (K-CREB and M1-CREB) and siRNA transfection, which disrupt the factor activity and expression, respectively, inhibit antimycin-A-induced triglyceride accumulation.	Triglycerides	260-272	cAMP responsive element binding protein 1	Mus musculus	118-122	
16537646-8	2006	We also demonstrate that overexpression of two dominant negative mutants of the cAMP-response element-binding protein CREB (K-CREB and M1-CREB) and siRNA transfection, which disrupt the factor activity and expression, respectively, inhibit antimycin-A-induced triglyceride accumulation.	Triglycerides	260-272	cAMP responsive element binding protein 1	Mus musculus	135-142	
16537646-9	2006	Furthermore, CREB knockdown with siRNA also downregulates the expression of several genes that contain cAMP-response element (CRE) sites in their promoter, among them one that is potentially involved in synthesis of triglycerides such as SCD1.	Triglycerides	216-229	cAMP responsive element binding protein 1	Mus musculus	13-17	
16537646-10	2006	These results highlight a new role for CREB in the control of triglyceride metabolism during the adaptative response of preadipocytes to mitochondrial dysfunction.	Triglycerides	62-74	cAMP responsive element binding protein 1	Mus musculus	39-43	
10629058-8	2000	Inducible expression of VP16-CREB alone was sufficient to initiate adipogenesis as determined by triacylglycerol storage, cell morphology, and the expression of two adipocyte marker genes, peroxisome proliferator activated receptor gamma 2, and fatty acid binding protein.	Triglycerides	97-112	cAMP responsive element binding protein 1	Mus musculus	24-33