PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33500106-6	2021	Delta-6-desaturase (D6D) activity correlated inversely with eIS (r = -0.32,p = 6.6*10-5) and directly with triglycerides (r = 0.24, p = 0.003), adjusted for z-BMI, age and gender.	Triglycerides	107-120	fatty acid desaturase 2	Homo sapiens	0-18	
2511142-10	1989	Triglycerides of gamma linolenic acid have been considered to be of value in situations when there may be a reduced activity of delta-6-desaturase to transform linoleic acid to arachidonic acid.	Triglycerides	0-13	fatty acid desaturase 2	Homo sapiens	128-146	
33500106-6	2021	Delta-6-desaturase (D6D) activity correlated inversely with eIS (r = -0.32,p = 6.6*10-5) and directly with triglycerides (r = 0.24, p = 0.003), adjusted for z-BMI, age and gender.	Triglycerides	107-120	fatty acid desaturase 2	Homo sapiens	20-23	
29779171-5	2019	RESULTS: Carriers of FADS1 rs174547 and FADS2 rs2845573 minor alleles had lower serum HDL-cholesterol and glucose levels and higher triglyceride levels than those with major alleles.	Triglycerides	132-144	fatty acid desaturase 2	Homo sapiens	40-45	
32525743-10	2020	For example, hypermethylation of cg11250194 (FADS2) was associated with lower triglyceride concentrations (MR p-value = 1.5x10-14) and hypermethylation of cg02079413 (SNORA54; NAP1L4) was associated with BMI (corrected MR p-value = 1x10-6).	Triglycerides	78-90	fatty acid desaturase 2	Homo sapiens	45-50	
29795460-7	2019	Haplotype analyses revealed three blocks (Pint < 0.011) that could drive the interaction between FADS and n-3 PUFA on triglycerides; functional annotation of these regions showed that each block harbours a number of highly functional regulatory variants; FADS2 rs5792235 demonstrated the highest functionality score.	Triglycerides	121-134	fatty acid desaturase 2	Homo sapiens	258-263	
29779171-6	2019	Ansan/Ansung cohort individuals with FADS1 minor alleles or haplotypes of FADS1 and FADS2 minor alleles had increased risk of MetS, including lower serum HDL-cholesterol and triglyceride levels and blood pressure after adjusting for MetS-related confounders.	Triglycerides	174-186	fatty acid desaturase 2	Homo sapiens	84-89	
30170993-2	2018	Genome-wide association studies have reported associations between FADS1-FADS2 polymorphisms and the plasma concentrations of PUFAs, HDL- and LDL-cholesterol, and triglycerides.	Triglycerides	163-176	fatty acid desaturase 2	Homo sapiens	73-78	
28774683-2	2018	Genome-wide associations studies (GWAS) reported associations between polymorphisms in FADS1-FADS2 and variations in plasma concentrations of PUFAs, HDL- and LDL-cholesterol and triglycerides.	Triglycerides	178-191	fatty acid desaturase 2	Homo sapiens	93-98	
27273350-8	2016	Minor allele carriers of rs174574, rs174576 and rs174578 (FADS2) and rs174455 (FADS3) exhibited significant higher triglyceride levels, whereas minor allele carriers for rs174449 and rs174455 (FADS3) exhibited significant higher total- and LDL-cholesterol levels compared to the more common variant.	Triglycerides	115-127	fatty acid desaturase 2	Homo sapiens	58-63	
26892124-8	2016	Estimated stearoyl-CoA-desaturase and Delta6-desaturase activities in plasma TG and PL were directly associated with CRS, whereas estimated elongase activity in plasma TG and PL was inversely related to CRS.	Triglycerides	77-79	fatty acid desaturase 2	Homo sapiens	22-33	
23419767-5	2013	D6D and D5D activities, but not SCD activity, were significantly associated with triglyceride levels, high-density lipoprotein cholesterol levels and insulin resistance in both sexes, and with CRP levels in boys.	Triglycerides	81-93	fatty acid desaturase 2	Homo sapiens	0-3	
22629455-12	2012	CONCLUSION: Total cholesterol, HDL, LDL and triglyceride concentrations may be influenced by the FADS1 FADS2 genotype already in 10 year old children.	Triglycerides	44-56	fatty acid desaturase 2	Homo sapiens	103-108	
20364269-2	2010	We investigated the associations between the SNPs in FADS1/FADS2 and plasma concentrations of triglycerides, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) in two Asian groups, i.e., Japanese and Mongolians.	Triglycerides	94-107	fatty acid desaturase 2	Homo sapiens	59-64	
19083494-8	2008	delta-6 desaturase activity showed positive associations with BMI, systolic blood pressure, triacylglycerol, and the homeostasis model assessment of insulin resistance (P <or= .045).	Triglycerides	92-107	fatty acid desaturase 2	Homo sapiens	0-18	
11916926-7	2002	In accordance with the decrease of Delta-6 desaturase mRNA, there was a significant decrease in the omega6-C18:3/C18:2 ratio down to 47.4 +/- 7.5% in cholesterol esters, 54.2 +/- 7.4% in phospholipids, 56.7 +/- 6.5% in nonesterified fatty acids, and 67.7 +/- 5.9% in triglycerides.	Triglycerides	267-280	fatty acid desaturase 2	Homo sapiens	35-53