PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22492582-0 2012 Site-specific fluorescein labeling of human insulin. Fluorescein 14-25 insulin Homo sapiens 44-51 25892399-4 2015 For the cellular uptake study, fluorescein-labeled insulin or DCK were prepared according to a standard protocol and applied to Caco-2 or MDCK cell lines. Fluorescein 31-42 insulin Homo sapiens 51-58 22492582-1 2012 Three fluorescein derivatives of human insulin (HI, 1) labeled at positions N(alphaA1) , N(alphaB1) and N(epsilonB29) respectively, were synthesized using an N-trifluoroacetyl-based protecting group scheme. Fluorescein 6-17 insulin Homo sapiens 39-46 11695899-5 2001 Furthermore, analogues of the related phenol red and fluorescein molecules fully displace insulin from the IR ectodomain, however, without insulin agonistic effects. Fluorescein 53-64 insulin Homo sapiens 90-97 19441323-1 2009 The sugar sensitive microcapsules were prepared by a layer-by-layer deposition of concanavalin A (Con A) and glycogen on a calcium carbonate particle containing fluorescein-labeled insulin (F-insulin). Fluorescein 161-172 insulin Homo sapiens 181-188 22087468-7 2012 Separation of two dyes, fluorescein and FLCA, with baseline resolution is achieved in less than 3 min and separation of two proteins, insulin and casein is demonstrated. Fluorescein 24-35 insulin Homo sapiens 134-141 14602192-6 2003 At equilibrium conditions fluorescein-labeled insulin could only be detected in the presence of the colloid; the detection limit was 250 nM, and a fourfold increase in fluorescence was observed upon real time monitoring. Fluorescein 26-37 insulin Homo sapiens 46-53 12100989-1 2002 Transdermal insulin transport by electroporation was measured using porcine epidermis and fluorescein-labeled insulin. Fluorescein 90-101 insulin Homo sapiens 12-19 7531408-5 1994 Intracellular staining was accomplished using a fluorescein conjugated anti-insulin monoclonal antibody. Fluorescein 48-59 insulin Homo sapiens 76-83 10332061-7 1999 Studies using fluorescein-labeled insulin revealed that insulin was uniformly distributed in the beads regardless of polymer MW. Fluorescein 14-25 insulin Homo sapiens 34-41 10332061-7 1999 Studies using fluorescein-labeled insulin revealed that insulin was uniformly distributed in the beads regardless of polymer MW. Fluorescein 14-25 insulin Homo sapiens 56-63 8916449-2 1996 In the assay, solutions of fluorescein-labeled insulin (FITC-insulin), monoclonal anti-insulin, and sample containing insulin are pumped into a cross where they begin to mix. Fluorescein 27-38 insulin Homo sapiens 47-54 3002090-0 1985 The blood-retinal barrier permeability to fluorescein in juvenile diabetics treated with continuous subcutaneous insulin infusion. Fluorescein 42-53 insulin Homo sapiens 113-120 18964705-5 1989 Anti-porcine insulin antibody and fluorescein-labelled bovine insulin were successfully used for the determination of both human insulin and bovine insulin. Fluorescein 34-45 insulin Homo sapiens 62-69 3293866-7 1988 Specific fluorescein-labeled anti-insulin antibodies revealed staining in 60-80% of the cultured cells isolated from the patient"s pancreas, while electron microscopy disclosed insulin storage granules in about 80%. Fluorescein 9-20 insulin Homo sapiens 34-41 3428242-1 1987 The interaction of a fluorescein-labelled insulin and of cytochrome C with the air-solution interface and with lipid monolayers at the air-solution interface has been studied by measuring the change in surface pressure at constant area and by reflection spectroscopy. Fluorescein 21-32 insulin Homo sapiens 42-49 2415418-6 1985 The preparation with a fluorescein/protein ratio of approximately 1.0 was found to have the highest affinity to the receptor, the highest biological activity (approximately 50% of native insulin), and similar antigenicity as native insulin. Fluorescein 23-34 insulin Homo sapiens 187-194 24234714-4 1993 The technique of total internal reflection with fluorescence recovery after photobleaching (TIR-FRAP) was used here to study these rate parameters of fluorescein-labeled insulin (f-insulin) interacting with erythrocyte ghosts. Fluorescein 150-161 insulin Homo sapiens 170-177 24234714-4 1993 The technique of total internal reflection with fluorescence recovery after photobleaching (TIR-FRAP) was used here to study these rate parameters of fluorescein-labeled insulin (f-insulin) interacting with erythrocyte ghosts. Fluorescein 150-161 insulin Homo sapiens 181-188 6759217-4 1982 Among 11 IDD treated intensively with home blood glucose monitoring and pumped subcutaneous insulin or three or more injections daily, hemoglobin A1C fell dramatically (10.4 +/- 0.7% to 7.5 +/- 0.2%) and anterior chamber fluorescein concentration decreased (73.9 +/- 7.7 to 49.5 +/- 5.3 ng/ml). Fluorescein 221-232 insulin Homo sapiens 92-99 6628836-3 1983 Mean vitreous fluorescein concentration in the CF patients whose hyperglycemia was treated with insulin (11.79 ng/ml) was significantly higher than in CF patients with normal carbohydrate tolerance (6.98 ng/ml, P less than 0.005). Fluorescein 14-25 insulin Homo sapiens 96-103 7188047-1 1982 Restoration of near-normal glucose metabolism with the insulin pump reduces retinal fluorescein leakage and microalbuminuria in diabetes. Fluorescein 84-95 insulin Homo sapiens 55-62 7021578-0 1981 Fluorescein-isothiocyanated insulin interactions with human platelets. Fluorescein 0-11 insulin Homo sapiens 28-35