PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11409873-4 2001 The purpose of this study was to examine the role of MRP1 in the brain distribution of a model organic anion, fluorescein. Fluorescein 110-121 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 53-57 14502537-10 2003 Dexloxiglumide increased MRP1-substrate fluorescein uptake 4-fold, and fluorescein increased dexloxiglumide uptake 1.8-fold. Fluorescein 40-51 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 25-29 11409873-5 2001 The substrate specificity of MRP1 for fluorescein was initially determined by examining the accumulation of fluorescein in MDCKII MRP1-transfected cells. Fluorescein 38-49 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 29-33 11409873-5 2001 The substrate specificity of MRP1 for fluorescein was initially determined by examining the accumulation of fluorescein in MDCKII MRP1-transfected cells. Fluorescein 38-49 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 130-134 11409873-5 2001 The substrate specificity of MRP1 for fluorescein was initially determined by examining the accumulation of fluorescein in MDCKII MRP1-transfected cells. Fluorescein 108-119 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 29-33 11409873-5 2001 The substrate specificity of MRP1 for fluorescein was initially determined by examining the accumulation of fluorescein in MDCKII MRP1-transfected cells. Fluorescein 108-119 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 130-134 11409873-9 2001 In an in vivo study, after intravenous injection of fluorescein, the fluorescein brain-to-plasma concentration ratio in mrp1 knockout mice was not significantly different than that in wild-type mice. Fluorescein 52-63 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 120-124 11409873-9 2001 In an in vivo study, after intravenous injection of fluorescein, the fluorescein brain-to-plasma concentration ratio in mrp1 knockout mice was not significantly different than that in wild-type mice. Fluorescein 69-80 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 120-124 11409873-11 2001 These findings suggest that fluorescein is a substrate for MRP1. Fluorescein 28-39 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 59-63 11409873-12 2001 Furthermore, the in vivo study also suggests that MRP1 has a limited role in the transport and distribution of fluorescein in the brain. Fluorescein 111-122 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 50-54 11289130-4 2001 The reduced toxicity of 4A6 in MRP1-overexpressing cells was found to be associated with lower accumulation of a fluorescein-labeled derivative of this peptide. Fluorescein 113-124 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 31-35