PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22901180-5 2012 In vivo, an animal study was set out in which BALB/C nude mice bearing tumors were treated with lentivirus mediated expression of Dm-dNKmut with the pyrimidine nucleoside analog brivudine (BVDU, (E)-5-(2-bromovinyl)-(2-deoxyuridine). brivudine 178-187 deoxyribonucleoside kinase Drosophila melanogaster 130-139 23254508-4 2013 Furthermore, BALB/C nude mice bearing tumors were treated with Dm-dNK mediated with the pyrimidine nucleoside analog, brivudine [BVDU, (E)-5-(2-bromovinyl)-2"-deoxyuridine]. brivudine 142-151 deoxyribonucleoside kinase Drosophila melanogaster 75-81 23254508-4 2013 Furthermore, BALB/C nude mice bearing tumors were treated with Dm-dNK mediated with the pyrimidine nucleoside analog, brivudine [BVDU, (E)-5-(2-bromovinyl)-2"-deoxyuridine]. brivudine 159-195 deoxyribonucleoside kinase Drosophila melanogaster 75-81 23000515-7 2013 SG500-dNK combined with the chemotherapeutics (E)-5-(2-bromovinyl)-2"-deoxyuridine (Bvdu) and 2",2"-difluoro-deoxycytidine (dFdC) resulted in synergistically enhanced cell killing and greatly improved antitumor efficacy in vitro or in breast xenografts in vivo. brivudine 46-82 deoxyribonucleoside kinase Drosophila melanogaster 6-9 22901180-5 2012 In vivo, an animal study was set out in which BALB/C nude mice bearing tumors were treated with lentivirus mediated expression of Dm-dNKmut with the pyrimidine nucleoside analog brivudine (BVDU, (E)-5-(2-bromovinyl)-(2-deoxyuridine). brivudine 195-231 deoxyribonucleoside kinase Drosophila melanogaster 130-139 18384378-4 2008 In this study we present crystal structures of dNK complexed with four different nucleoside analogs (floxuridine, brivudine, zidovudine and zalcitabine) and relate them to the binding of substrate and feedback inhibitors. brivudine 114-123 deoxyribonucleoside kinase Drosophila melanogaster 47-50 12626708-5 2003 In addition, Ag-dNK could also phosphorylate some medically interesting nucleoside analogs, like stavudine (D4T), 2-chloro-deoxyadenosine (CdA) and 5-bromo-vinyl-deoxyuridine (BVDU). brivudine 176-180 deoxyribonucleoside kinase Drosophila melanogaster 16-19 11455012-8 2001 These findings indicate that BVDU phosphorylated by Dm-dNK in transduced cancer cells may also induce bystander cell death in certain cell lines. brivudine 29-33 deoxyribonucleoside kinase Drosophila melanogaster 52-58 10993893-7 2000 The cells expressing Dm-dNK exhibited increased sensitivity to several cytotoxic nucleoside analogs, such as 1-beta-d-arabinofuranosylcytosine, 1-beta-d-arabinofuranosylthymine, (E)-5-(2-bromovinyl)-2"-deoxyuridine, 2-chloro-2"-deoxyadenosine, and 2",2"-difluorodeoxycytidine. brivudine 178-214 deoxyribonucleoside kinase Drosophila melanogaster 21-27