PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26359088-9 2015 Moreover, the increase in glycerol release induced by widdrol was almost completely blocked by PKC, MEK, and ERK inhibitors. Glycerol 26-34 proline rich transmembrane protein 2 Homo sapiens 95-98 15369389-3 2004 The constrained glycerol backbone of DAG-lactones, when combined with highly branched alkyl chains, has engendered a series of DAG-lactone ligands capable of binding protein kinase C (PK-C) with affinities that approximate those of phorbol esters. Glycerol 16-24 proline rich transmembrane protein 2 Homo sapiens 166-182 21975067-2 2011 The endogenous PKC activator diacylglycerol contains two long carbon chains, which are attached to the glycerol moiety via ester linkage. Glycerol 35-43 proline rich transmembrane protein 2 Homo sapiens 15-18 15369389-3 2004 The constrained glycerol backbone of DAG-lactones, when combined with highly branched alkyl chains, has engendered a series of DAG-lactone ligands capable of binding protein kinase C (PK-C) with affinities that approximate those of phorbol esters. Glycerol 16-24 proline rich transmembrane protein 2 Homo sapiens 184-188 12809530-2 2003 We have developed a series of 4,4-disubstituted-gamma-butyrolactones, which contain a constrained glycerol backbone (DAG-lactones) and behave as potent and selective activating ligands of PK-C with affinities that approach those of the structurally complex natural product agonists, such as the phorbol esters. Glycerol 98-106 proline rich transmembrane protein 2 Homo sapiens 188-192