PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19424415-4	2009	Deletion of the glycerol biosynthesis genes GPD1, GPD2, or RHR2, among the most up-regulated in long-lived sch9Delta, tor1Delta, and ras2Delta mutants, was sufficient to reverse chronological life span extension in sch9Delta mutants, suggesting that glycerol production, in addition to the regulation of stress resistance systems, optimizes life span extension.	Glycerol	16-24	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	59-63	
19424415-4	2009	Deletion of the glycerol biosynthesis genes GPD1, GPD2, or RHR2, among the most up-regulated in long-lived sch9Delta, tor1Delta, and ras2Delta mutants, was sufficient to reverse chronological life span extension in sch9Delta mutants, suggesting that glycerol production, in addition to the regulation of stress resistance systems, optimizes life span extension.	Glycerol	250-258	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	59-63	
17390123-7	2007	Both growth on glycerol-based medium and overexpression of SSD1, FLO8 or WSC3 had additive suppressing effect on CFW sensitivity of the gpp1gpp2 mutant strain.	Glycerol	15-23	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	136-144	
11676566-5	2001	In contrast, overexpression of GPP1, encoding glycerol 3-phosphatase (Gpp1p), did not enhance glycerol production.	Glycerol	46-54	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	31-35	
11676566-5	2001	In contrast, overexpression of GPP1, encoding glycerol 3-phosphatase (Gpp1p), did not enhance glycerol production.	Glycerol	46-54	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	70-75	
11058591-0	2001	The yeast glycerol 3-phosphatases Gpp1p and Gpp2p are required for glycerol biosynthesis and differentially involved in the cellular responses to osmotic, anaerobic, and oxidative stress.	Glycerol	10-18	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	34-39	
11058591-2	2001	Mutants lacking both GPP1 and GPP2 are devoid of glycerol 3-phosphatase activity and produce only a small amount of glycerol, confirming the essential role for this enzyme in glycerol biosynthesis.	Glycerol	49-57	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	21-25	
11058591-2	2001	Mutants lacking both GPP1 and GPP2 are devoid of glycerol 3-phosphatase activity and produce only a small amount of glycerol, confirming the essential role for this enzyme in glycerol biosynthesis.	Glycerol	116-124	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	21-25	
11058591-4	2001	Previous studies have shown that expression of both GPP1 and GPP2 is induced under hyperosmotic stress and that induction partially depends on the HOG (high osmolarity glycerol) pathway.	Glycerol	168-176	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	52-56	
10931288-2	2000	Consistently, mutant strains gpd1gpd2 and gpp1gpp2, which are devoid of the main glycerol biosynthesis pathway, have been shown to be osmosensitive.	Glycerol	81-89	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	42-50	
35137036-7	2022	Expression of S. cerevisiae GPD2, which encodes NAD+-dependent glycerol-3-phosphate dehydrogenase, and GPP1 supported increased glycerol production by oxygen-limited chemostat cultures of O. parapolymorpha.	Glycerol	128-136	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	103-107	
31395335-5	2019	Here, we show that Ste20 and Cla4 not only stimulate transcription, they also bind to the glycerol biosynthesis enzymes Gpd1, Gpp1 and Gpp2.	Glycerol	90-98	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	126-130	
26187821-5	2015	Of the eight proteins involved in glycerol metabolism, Gut2p was detected only under BFC while Pgs1p and Rhr2p were under NBFC.	Glycerol	34-42	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	105-110	
11113971-7	2000	At low demand for NADH reoxidation via glycerol formation, the GPD1, GPD2, GPP1, and GPP2 genes were all expressed at basal levels.	Glycerol	39-47	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	75-79	
26338116-2	2015	We have implemented an RT-qPCR (Reverse Transcription-quantitative PCR) methodology with a preventive evaluation of candidate reference genes, to study six target genes related to glycerol synthesis (GPD1, GPD2, GPP2 and GPP1) and flux (STL1 and FPS1), and three ALD genes coding for aldehyde dehydrogenase involved in redox equilibrium via acetate production.	Glycerol	180-188	glycerol-1-phosphatase RHR2	Saccharomyces cerevisiae S288C	221-225