PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19424415-4 2009 Deletion of the glycerol biosynthesis genes GPD1, GPD2, or RHR2, among the most up-regulated in long-lived sch9Delta, tor1Delta, and ras2Delta mutants, was sufficient to reverse chronological life span extension in sch9Delta mutants, suggesting that glycerol production, in addition to the regulation of stress resistance systems, optimizes life span extension. Glycerol 16-24 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 59-63 19424415-4 2009 Deletion of the glycerol biosynthesis genes GPD1, GPD2, or RHR2, among the most up-regulated in long-lived sch9Delta, tor1Delta, and ras2Delta mutants, was sufficient to reverse chronological life span extension in sch9Delta mutants, suggesting that glycerol production, in addition to the regulation of stress resistance systems, optimizes life span extension. Glycerol 250-258 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 59-63 17390123-7 2007 Both growth on glycerol-based medium and overexpression of SSD1, FLO8 or WSC3 had additive suppressing effect on CFW sensitivity of the gpp1gpp2 mutant strain. Glycerol 15-23 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 136-144 11676566-5 2001 In contrast, overexpression of GPP1, encoding glycerol 3-phosphatase (Gpp1p), did not enhance glycerol production. Glycerol 46-54 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 31-35 11676566-5 2001 In contrast, overexpression of GPP1, encoding glycerol 3-phosphatase (Gpp1p), did not enhance glycerol production. Glycerol 46-54 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 70-75 11058591-0 2001 The yeast glycerol 3-phosphatases Gpp1p and Gpp2p are required for glycerol biosynthesis and differentially involved in the cellular responses to osmotic, anaerobic, and oxidative stress. Glycerol 10-18 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 34-39 11058591-2 2001 Mutants lacking both GPP1 and GPP2 are devoid of glycerol 3-phosphatase activity and produce only a small amount of glycerol, confirming the essential role for this enzyme in glycerol biosynthesis. Glycerol 49-57 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 21-25 11058591-2 2001 Mutants lacking both GPP1 and GPP2 are devoid of glycerol 3-phosphatase activity and produce only a small amount of glycerol, confirming the essential role for this enzyme in glycerol biosynthesis. Glycerol 116-124 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 21-25 11058591-4 2001 Previous studies have shown that expression of both GPP1 and GPP2 is induced under hyperosmotic stress and that induction partially depends on the HOG (high osmolarity glycerol) pathway. Glycerol 168-176 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 52-56 10931288-2 2000 Consistently, mutant strains gpd1gpd2 and gpp1gpp2, which are devoid of the main glycerol biosynthesis pathway, have been shown to be osmosensitive. Glycerol 81-89 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 42-50 11113971-7 2000 At low demand for NADH reoxidation via glycerol formation, the GPD1, GPD2, GPP1, and GPP2 genes were all expressed at basal levels. Glycerol 39-47 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 75-79 35137036-7 2022 Expression of S. cerevisiae GPD2, which encodes NAD+-dependent glycerol-3-phosphate dehydrogenase, and GPP1 supported increased glycerol production by oxygen-limited chemostat cultures of O. parapolymorpha. Glycerol 128-136 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 103-107 26338116-2 2015 We have implemented an RT-qPCR (Reverse Transcription-quantitative PCR) methodology with a preventive evaluation of candidate reference genes, to study six target genes related to glycerol synthesis (GPD1, GPD2, GPP2 and GPP1) and flux (STL1 and FPS1), and three ALD genes coding for aldehyde dehydrogenase involved in redox equilibrium via acetate production. Glycerol 180-188 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 221-225 31395335-5 2019 Here, we show that Ste20 and Cla4 not only stimulate transcription, they also bind to the glycerol biosynthesis enzymes Gpd1, Gpp1 and Gpp2. Glycerol 90-98 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 126-130 26187821-5 2015 Of the eight proteins involved in glycerol metabolism, Gut2p was detected only under BFC while Pgs1p and Rhr2p were under NBFC. Glycerol 34-42 glycerol-1-phosphatase RHR2 Saccharomyces cerevisiae S288C 105-110