PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31849880-0 2019 The Glycerol Phosphatase Gpp2: A Link to Osmotic Stress, Sulfur Assimilation and Virulence in Cryptococcus neoformans. Glycerol 4-12 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 25-29 24732094-5 2014 This approach revealed that osmotic up-regulation of only two Hog1-dependent glycerol biosynthesis genes, GPD1 and GPP2, is sufficient for successful osmoadaptation. Glycerol 77-85 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 115-119 31395335-5 2019 Here, we show that Ste20 and Cla4 not only stimulate transcription, they also bind to the glycerol biosynthesis enzymes Gpd1, Gpp1 and Gpp2. Glycerol 90-98 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 135-139 26441028-2 2015 Glycerol, a key precursor for 3-HP biosynthesis was produced by overexpression of the GPD1 and GPP2 genes from Saccharomyces cerevisiae. Glycerol 0-8 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 95-99 26338116-2 2015 We have implemented an RT-qPCR (Reverse Transcription-quantitative PCR) methodology with a preventive evaluation of candidate reference genes, to study six target genes related to glycerol synthesis (GPD1, GPD2, GPP2 and GPP1) and flux (STL1 and FPS1), and three ALD genes coding for aldehyde dehydrogenase involved in redox equilibrium via acetate production. Glycerol 180-188 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 212-216 28280870-8 2017 To increase glycerol production and accumulation from glucose, we lowered the expression of TPI1 gene coding for triose phosphate isomerase; overexpressed the fused gene consisting the GPD1 and GPP2 parts coding for glycerol-3-phosphate dehydrogenase and glycerol-3-phosphate phosphatase, respectively; overexpressed the engineered FPS1 gene that codes for aquaglyceroporin; and overexpressed the truncated gene ILV2 that codes for acetolactate synthase. Glycerol 12-20 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 194-198 11058591-0 2001 The yeast glycerol 3-phosphatases Gpp1p and Gpp2p are required for glycerol biosynthesis and differentially involved in the cellular responses to osmotic, anaerobic, and oxidative stress. Glycerol 10-18 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 44-49 23762021-4 2013 The Hog1 kinase stimulates transcription of genes encoding enzymes required for glycerol production (Gpd1, Gpp2) and glycerol import (Stl1) and activates a regulatory enzyme in glycolysis (Pfk26/27). Glycerol 80-88 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 107-111 17113805-1 2007 The Saccharomyces cerevisiae glycerol pathway (GPD1 and GPP2) was evolved in vivo in Escherichia coli. Glycerol 29-37 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 56-60 14734031-5 2004 When the ORFs of the S. cerevisiae glycerol 3-phosphatase gene (GPP2) and ZrGPD1 were simultaneously expressed, glycerol production increased, compared with that in yeast expressing only ZrGPD1. Glycerol 35-43 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 64-68 16943074-4 2006 Genes involved in ethanol production (PDC genes and ADH1), in glycerol synthesis (GPD1 and HOR2), and in low-affinity hexose transporters (HXT1 and HXT3) were up-regulated at the beginning of model dough-fermentation. Glycerol 62-70 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 91-95 11058591-2 2001 Mutants lacking both GPP1 and GPP2 are devoid of glycerol 3-phosphatase activity and produce only a small amount of glycerol, confirming the essential role for this enzyme in glycerol biosynthesis. Glycerol 49-57 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 30-34 11058591-2 2001 Mutants lacking both GPP1 and GPP2 are devoid of glycerol 3-phosphatase activity and produce only a small amount of glycerol, confirming the essential role for this enzyme in glycerol biosynthesis. Glycerol 116-124 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 30-34 11058591-4 2001 Previous studies have shown that expression of both GPP1 and GPP2 is induced under hyperosmotic stress and that induction partially depends on the HOG (high osmolarity glycerol) pathway. Glycerol 168-176 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 61-65 11058591-11 2001 Consistent with a role for glycerol 3-phosphatase in protection against oxidative stress, expression of GPP2 is induced in the presence of paraquat. Glycerol 27-35 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 104-108 10641035-4 2000 Proteins with increased expression during growth under sodium chloride stress could be grouped into three classes with respect to PKA activity, with the glycerol metabolic proteins GPD1, GPP2 and DAK1 standing out as independent of PKA. Glycerol 153-161 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 187-191 11113971-7 2000 At low demand for NADH reoxidation via glycerol formation, the GPD1, GPD2, GPP1, and GPP2 genes were all expressed at basal levels. Glycerol 39-47 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 85-89 9042961-5 1997 Northern analysis of the salt induced transcription of GPD1 and GPP2, encoding the cytosolic glycerol-3-phosphate dehydrogenase and glycerol-3-phosphatase involved in the osmostress induced glycerol production, demonstrated an about 20-fold PBS2-dependent transient activation, in agreement with the previously reported transient nature of the signal transduced by the HOG pathway. Glycerol 93-101 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 64-68 10409737-5 1999 hot1 single mutants are specifically compromised in the transient induction of GPD1 and GPP2, which encode enzymes involved in glycerol biosynthesis, and exhibit delayed glycerol accumulation after stress exposure. Glycerol 127-135 glycerol-1-phosphatase HOR2 Saccharomyces cerevisiae S288C 88-92