PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23518242-9	2013	Introduction of the ssk1(E330N...K356N) allele in the industrial reference strain resulted in stronger reduction of the glycerol/ethanol ratio compared to SSK1 deletion and also compromised volumetric productivity and osmotolerance less.	Glycerol	120-128	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	20-24	
12944490-3	2003	Unphosphorylated Ssk1p binds to and activates the Ssk2p mitogen-activated protein (MAP) kinase kinase kinase, which in turn activates the downstream components of the high-osmolarity glycerol response (HOG) MAP kinase cascade.	Glycerol	183-191	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	17-22	
23065846-10	2012	From these results, we postulated that the Sln1-Ypd1-Ssk1 branch of the high-osmolality glycerol (HOG) pathway and plasma membrane sensors of the cell wall integrity (CWI) pathway detect cell wall stresses caused by HM-1.	Glycerol	88-96	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	53-57	
19618914-5	2009	In this study, we examined the individual and combined effects of NaCl and glycerol on phosphotransfer rates within the SLN1-YPD1-SSK1 phosphorelay.	Glycerol	75-83	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	130-134	
18573873-0	2008	Phosphorylated Ssk1 prevents unphosphorylated Ssk1 from activating the Ssk2 mitogen-activated protein kinase kinase kinase in the yeast high-osmolarity glycerol osmoregulatory pathway.	Glycerol	152-160	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	15-19	
18573873-0	2008	Phosphorylated Ssk1 prevents unphosphorylated Ssk1 from activating the Ssk2 mitogen-activated protein kinase kinase kinase in the yeast high-osmolarity glycerol osmoregulatory pathway.	Glycerol	152-160	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	46-50	
9882653-2	1999	The SLN1-YPD1-SSK1 phosphorelay regulates a downstream mitogen-activated protein kinase cascade which ultimately controls the concentration of glycerol within the cell under hyperosmotic stress conditions.	Glycerol	143-151	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	14-18	
9790591-1	1998	Activation and control of the yeast HOG (High Osmolarity Glycerol) MAP kinase cascade is accomplished, in part, by a two-component sensory-response circuit comprised of the osmosensing histidine protein kinase Sln1p, the phospho-relay protein Ypd1p, and the response regulator protein Ssk1p.	Glycerol	57-65	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	285-290	
29249052-3	2018	The best known of these fungal transduction pathways remains the Sln1(HHK)-Ypd1(HPt)-Ssk1(RR) system that governs the high-osmolarity glycerol (HOG) mitogen-activated protein kinase (MAPK) pathway for osmo-adaptation in Saccharomyces cerevisiae.	Glycerol	134-142	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	85-89	
31642125-6	2019	Upon detecting hyperosmotic stress, Ssk1 rapidly dephosphorylates and activates the high-osmolarity glycerol (HOG) pathway, initiating a response.	Glycerol	100-108	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	36-40	
26396653-5	2014	We investigate the Sln1-Ypd1-Ssk1-phosphorelay as a module in the high-osmolarity glycerol pathway by incorporating a stochastic model.	Glycerol	82-90	mitogen-activated protein kinase kinase kinase SSK1	Saccharomyces cerevisiae S288C	29-33