PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12392719-0 2002 The effect of glycerol on cytochrome P450scc (CYP11A1) spin state, activity, and hydration. Glycerol 14-22 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 26-44 12392719-0 2002 The effect of glycerol on cytochrome P450scc (CYP11A1) spin state, activity, and hydration. Glycerol 14-22 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 46-53 12392719-4 2002 Glycerol weakened adrenodoxin binding to P450scc but had no effect on CO or 20alpha,22R-dihydroxycholesterol binding. Glycerol 0-8 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 41-48 12392719-5 2002 Cytochrome P450scc activity was inhibited by glycerol with the K(1/2) for inhibition being substrate-dependent. Glycerol 45-53 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 0-18 12392719-6 2002 The osmotic stress exerted by glycerol on P450scc resulted in decreases in P450scc molecular volume for both the transition to low spin state and the inhibition of activity. Glycerol 30-38 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 42-49 12392719-6 2002 The osmotic stress exerted by glycerol on P450scc resulted in decreases in P450scc molecular volume for both the transition to low spin state and the inhibition of activity. Glycerol 30-38 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 75-82 12392719-8 2002 The dehydration of P450scc by osmotic stress provides an explanation for the effects of glycerol on P450scc spin transition and activity. Glycerol 88-96 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 19-26 12392719-8 2002 The dehydration of P450scc by osmotic stress provides an explanation for the effects of glycerol on P450scc spin transition and activity. Glycerol 88-96 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 100-107