PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32528559-2	2017	We have previously found that in mouse keratinocytes, the lipid-metabolizing enzyme phospholipase D2 (PLD2) is associated with the aquaglyceroporin, aquaporin 3 (AQP3), an efficient transporter of glycerol.	Glycerol	197-205	phospholipase D2	Mus musculus	84-100	
32528559-2	2017	We have previously found that in mouse keratinocytes, the lipid-metabolizing enzyme phospholipase D2 (PLD2) is associated with the aquaglyceroporin, aquaporin 3 (AQP3), an efficient transporter of glycerol.	Glycerol	197-205	phospholipase D2	Mus musculus	102-106	
32528559-5	2017	Objective: We hypothesized that the differentiative effects of this PLD2/AQP3/PG signaling cascade, in which AQP3 mediates the transport of glycerol into keratinocytes followed by its PLD2-catalyzed conversion to PG, are mediated by protein kinase CbetaII (PKCbetaII), which contains a PG-binding domain in its carboxy-terminus.	Glycerol	140-148	phospholipase D2	Mus musculus	68-72	
32528559-5	2017	Objective: We hypothesized that the differentiative effects of this PLD2/AQP3/PG signaling cascade, in which AQP3 mediates the transport of glycerol into keratinocytes followed by its PLD2-catalyzed conversion to PG, are mediated by protein kinase CbetaII (PKCbetaII), which contains a PG-binding domain in its carboxy-terminus.	Glycerol	140-148	phospholipase D2	Mus musculus	184-188	
14675200-3	2003	Whether aquaporin 3 and its glycerol transporting capacity are involved in regulating keratinocyte function, we have previously shown that phospholipase D2 can metabolize phospholipids in the presence of glycerol to yield phosphatidylglycerol.	Glycerol	204-212	phospholipase D2	Mus musculus	139-155	
14675200-3	2003	Whether aquaporin 3 and its glycerol transporting capacity are involved in regulating keratinocyte function, we have previously shown that phospholipase D2 can metabolize phospholipids in the presence of glycerol to yield phosphatidylglycerol.	Glycerol	28-36	phospholipase D2	Mus musculus	139-155	
14675200-6	2003	Our results suggest that aquaporin 3 and phospholipase D2 form a signaling module in lipid rafts, where aquaporin 3 transports glycerol to phospholipase D2 for the synthesis of phosphatidylglycerol.	Glycerol	127-135	phospholipase D2	Mus musculus	41-57	
14675200-6	2003	Our results suggest that aquaporin 3 and phospholipase D2 form a signaling module in lipid rafts, where aquaporin 3 transports glycerol to phospholipase D2 for the synthesis of phosphatidylglycerol.	Glycerol	127-135	phospholipase D2	Mus musculus	139-155	
34445455-3	2021	Glycerol entry into epidermal keratinocytes is facilitated by aquaglyceroporins like aquaporin-3 (AQP3), and its conversion to phosphatidylglycerol, a lipid messenger that promotes keratinocyte differentiation, requires the lipid-metabolizing enzyme phospholipase-D2 (PLD2).	Glycerol	0-8	phospholipase D2	Mus musculus	250-266	
34445455-8	2021	In contrast, the beneficial effects of oral glycerol required PLD2, with no improvement in psoriasiform lesions observed in PLD2 knockout mice.	Glycerol	44-52	phospholipase D2	Mus musculus	62-66	
34445455-9	2021	Our findings suggest that the ability of oral glycerol to improve psoriasiform lesions requires its PLD2-mediated conversion to phosphatidylglycerol, consistent with our previous report that phosphatidylglycerol itself improves psoriasiform lesions in this model.	Glycerol	46-54	phospholipase D2	Mus musculus	100-104	
32186673-3	2020	We previously demonstrated in epidermal keratinocytes that the glycerol channel aquaporin-3 (AQP3) interacts with phospholipase D2 (PLD2) to produce the signaling phospholipid phosphatidylglycerol (PG), which has been shown to accelerate skin wound healing in vivo.	Glycerol	63-71	phospholipase D2	Mus musculus	114-130	
32186673-3	2020	We previously demonstrated in epidermal keratinocytes that the glycerol channel aquaporin-3 (AQP3) interacts with phospholipase D2 (PLD2) to produce the signaling phospholipid phosphatidylglycerol (PG), which has been shown to accelerate skin wound healing in vivo.	Glycerol	63-71	phospholipase D2	Mus musculus	132-136