PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16380488-4 2006 Retroviral-mediated overexpression of ATGL in 3T3-L1 adipocytes increased basal and isoproterenol-stimulated glycerol and nonesterified fatty acid (NEFA) release, whereas siRNA-mediated knockdown of ATGL had the opposite effect. Glycerol 109-117 patatin-like phospholipase domain containing 2 Mus musculus 38-42 17114792-6 2007 Studies with ATGL-and HSL-directed small hairpin RNAs demonstrate that 1) ATGL activity is required for all PKA-stimulated FA and glycerol release in murine embryonic fibroblast adipocytes and 2) all PKA-stimulated FA release in the absence of HSL activity requires serine 517 phosphorylation. Glycerol 130-138 patatin-like phospholipase domain containing 2 Mus musculus 74-78 26055129-6 2015 RESULTS: We demonstrated that kinsenoside increased both adipose triglyceride lipase (ATGL)-mediated lipolysis, which was upregulated by AMP-activated protein kinase (AMPK) activation, and the hydrolysis of triglycerides to glycerol and fatty acids that require transportation into mitochondria for further beta-oxidation. Glycerol 224-232 patatin-like phospholipase domain containing 2 Mus musculus 57-84 26055129-6 2015 RESULTS: We demonstrated that kinsenoside increased both adipose triglyceride lipase (ATGL)-mediated lipolysis, which was upregulated by AMP-activated protein kinase (AMPK) activation, and the hydrolysis of triglycerides to glycerol and fatty acids that require transportation into mitochondria for further beta-oxidation. Glycerol 224-232 patatin-like phospholipase domain containing 2 Mus musculus 86-90 33077693-9 2020 Taken together, T1AM showed lipolytic potency via activation of the AMPK/FoxO1/ATGL/MGL axis for decomposing TGs to FFAs and glycerol and of the AMPK/ACC/CPT1 pathway in facilitating the mobilization of FFAs into the mitochondria, highlighting its therapeutic potential for the treatment of obesity. Glycerol 125-133 patatin-like phospholipase domain containing 2 Mus musculus 79-83 20336671-10 2010 Thus, these data suggest that increased ATGL signaling and reduced perilipin protein content may contribute to increased NEFA and glycerol levels in OVX mice, which are attenuated with E(2) treatment, but not by exercise. Glycerol 130-138 patatin-like phospholipase domain containing 2 Mus musculus 40-44 20023287-2 2010 Activation of ATGL initiates the hydrolytic catabolism of cellular triacylglycerol (TG) stores to glycerol and nonesterified fatty acids. Glycerol 74-82 patatin-like phospholipase domain containing 2 Mus musculus 14-18