PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6933904-1 1980 After single administration of potassium dichromate or glycerol, renal PAH excretion was markedly reduced in adult, but not in newborn and infant rats. Glycerol 55-63 phenylalanine hydroxylase Homo sapiens 71-74 31759357-10 2019 In the other solutions, viscosity increase (propylene glycol solutions) and acidic pH were observed mainly in the glycerol group. Glycerol 114-122 phenylalanine hydroxylase Homo sapiens 83-85 18769885-2 2008 Rescue of the enzyme activity of several recombinant hPAH mutant forms (I65T, R261Q, R270K and V388M) by low molecular weight compounds namely glycerol, trimethylamine N-oxide (TMAO) and sodium 4-phenylbutyrate (4-PB) was investigated using a prokaryotic expression model. Glycerol 143-151 phenylalanine hydroxylase Homo sapiens 53-57 11386853-0 2001 Glycerol increases the yield and activity of human phenylalanine hydroxylase mutant enzymes produced in a prokaryotic expression system. Glycerol 0-8 phenylalanine hydroxylase Homo sapiens 51-76 11386853-4 2001 Based on these observations, the effect of glycerol as a stabilizer agent of recombinant mutant forms of human phenylalanine hydroxylase enzymes (hPAH) produced in a prokaryotic expression system was investigated. Glycerol 43-51 phenylalanine hydroxylase Homo sapiens 111-136 11386853-4 2001 Based on these observations, the effect of glycerol as a stabilizer agent of recombinant mutant forms of human phenylalanine hydroxylase enzymes (hPAH) produced in a prokaryotic expression system was investigated. Glycerol 43-51 phenylalanine hydroxylase Homo sapiens 146-150 11386853-5 2001 The wild-type and two mutant forms of the hPAH protein (R270K and V388M) were expressed in the presence of glycerol in the culture medium. Glycerol 107-115 phenylalanine hydroxylase Homo sapiens 42-46 11386853-7 2001 The results obtained demonstrate that glycerol not only improved the yield of the soluble hPAH proteins (2- to 3-fold depending on the mutant enzyme) produced but also increased the specific activity of the purified recombinant enzymes. Glycerol 38-46 phenylalanine hydroxylase Homo sapiens 90-94 19937396-4 2010 In this study, we investigated the effect of different polyol compounds, e.g. glycerol, mannitol and PEG-6000 on the in vitro stability of purified hPAH produced in a heterologous prokaryotic expression system. Glycerol 78-86 phenylalanine hydroxylase Homo sapiens 148-152