PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20026076-1 2010 The calcium-triggered neurotransmitter release requires three SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins: synaptobrevin 2 (or vesicle-associated membrane protein 2) on the synaptic vesicle and syntaxin 1 and SNAP-25 (synaptosome-associated protein of 25 kDa) at the presynaptic plasma membrane. Ethylmaleimide 77-93 synaptosome associated protein 25 Homo sapiens 252-259 20026076-1 2010 The calcium-triggered neurotransmitter release requires three SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins: synaptobrevin 2 (or vesicle-associated membrane protein 2) on the synaptic vesicle and syntaxin 1 and SNAP-25 (synaptosome-associated protein of 25 kDa) at the presynaptic plasma membrane. Ethylmaleimide 77-93 synaptosome associated protein 25 Homo sapiens 261-301 20074052-1 2010 The SNARE (soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptor) protein SNAP-25 (25 kDa synaptosome-associated protein) is essential for regulated exocytosis in neuronal and neuroendocrine cells. Ethylmaleimide 19-35 synaptosome associated protein 25 Homo sapiens 98-105 19273577-2 2009 The soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) complex, composed of synaptobrevin 2, syntaxin and synaptosome-associated protein of 25 kDa or 23 kDa (SNAP25 or SNAP23), is essential in this process. Ethylmaleimide 12-28 synaptosome associated protein 25 Homo sapiens 193-199 18400989-5 2008 Cleavage of the soluble N-ethylmaleimide-sensitive-factor attachment protein receptor, synaptosomal-assiciated protein-25 (SNAP-25), with botulinum neurotoxin A impaired TG-induced increase in the surface expression of Orai1. Ethylmaleimide 24-40 synaptosome associated protein 25 Homo sapiens 87-121 18512733-2 2008 The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, which consists of Syntaxin1A, vesicle-associated membrane protein 2 (VAMP2) and synaptosomal-associated protein 25 kDa (SNAP25), plays an important role in the neurotransmitter system, and is therefore an attractive place to search for candidate genes for schizophrenia. Ethylmaleimide 14-28 synaptosome associated protein 25 Homo sapiens 171-209 18512733-2 2008 The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, which consists of Syntaxin1A, vesicle-associated membrane protein 2 (VAMP2) and synaptosomal-associated protein 25 kDa (SNAP25), plays an important role in the neurotransmitter system, and is therefore an attractive place to search for candidate genes for schizophrenia. Ethylmaleimide 14-28 synaptosome associated protein 25 Homo sapiens 211-217 18400989-5 2008 Cleavage of the soluble N-ethylmaleimide-sensitive-factor attachment protein receptor, synaptosomal-assiciated protein-25 (SNAP-25), with botulinum neurotoxin A impaired TG-induced increase in the surface expression of Orai1. Ethylmaleimide 24-40 synaptosome associated protein 25 Homo sapiens 123-130 17060155-1 2006 The paradigm for soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) function in mammalian cells has been built on advancements in our understanding of structural and biochemical aspects of synaptic vesicle exocytosis, involving specifically synaptobrevin, syntaxin 1 and SNAP25. Ethylmaleimide 25-41 synaptosome associated protein 25 Homo sapiens 298-304 17877635-4 2007 We report a loss of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein, synaptosome-associated protein 25 (SNAP 25) in HD brains of grades I-IV. Ethylmaleimide 32-48 synaptosome associated protein 25 Homo sapiens 111-144 17877635-4 2007 We report a loss of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein, synaptosome-associated protein 25 (SNAP 25) in HD brains of grades I-IV. Ethylmaleimide 32-48 synaptosome associated protein 25 Homo sapiens 146-153 17718519-2 2007 They block neurotransmitter release through specific proteolysis of one of the three soluble N-ethylmaleimide-sensitive-factor attachment protein receptors (SNAREs) SNAP-25, syntaxin, and synaptobrevin, which constitute part of the synaptic vesicle fusion machinery. Ethylmaleimide 93-109 synaptosome associated protein 25 Homo sapiens 165-172 16308274-1 2005 Neurosecretion is catalyzed by assembly of a soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE)-complex composed of SNAP-25, synaptobrevin and syntaxin. Ethylmaleimide 55-69 synaptosome associated protein 25 Homo sapiens 151-158 16888141-1 2006 Assembly of the soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) syntaxin 1, SNAP-25, and synaptobrevin 2 is thought to be the driving force for the exocytosis of synaptic vesicles. Ethylmaleimide 24-40 synaptosome associated protein 25 Homo sapiens 108-115 16648158-1 2006 Exocytotic release of neurotransmitters is mediated by the ternary soluble N-ethyl maleimide-sensitive fusion protein attachment protein receptors (SNAREs) complex, comprised of syntaxin (Sx), synaptosome-associated protein of 25 kDa (SNAP25), and synaptobrevin 2 (Sb2). Ethylmaleimide 75-92 synaptosome associated protein 25 Homo sapiens 193-233 16648158-1 2006 Exocytotic release of neurotransmitters is mediated by the ternary soluble N-ethyl maleimide-sensitive fusion protein attachment protein receptors (SNAREs) complex, comprised of syntaxin (Sx), synaptosome-associated protein of 25 kDa (SNAP25), and synaptobrevin 2 (Sb2). Ethylmaleimide 75-92 synaptosome associated protein 25 Homo sapiens 235-241 15721169-1 2005 The fusion of secretory vesicles with the plasma membrane requires the formation of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes between the vesicle-SNARE vesicle-associated membrane protein present on the vesicular membrane and the target-SNAREs SNAP-25 and syntaxin-1A. Ethylmaleimide 92-108 synaptosome associated protein 25 Homo sapiens 290-297 12496268-1 2003 Synaptic vesicle exocytosis requires three SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) proteins: syntaxin and SNAP-25 on the plasma membrane (t-SNAREs) and synaptobrevin/VAMP on the synaptic vesicles (v-SNARE). Ethylmaleimide 58-74 synaptosome associated protein 25 Homo sapiens 144-151 15471947-3 2005 Pancreatic beta-cell secretory granule exocytosis is mediated by the soluble N-ethylmaleimide-sensitive fusion protein attachment receptor protein complex of synaptosomal-associated protein of 25 kDa (SNAP-25), syntaxin 1, and vesicle-associated membrane protein 2. Ethylmaleimide 77-93 synaptosome associated protein 25 Homo sapiens 158-199 15471947-3 2005 Pancreatic beta-cell secretory granule exocytosis is mediated by the soluble N-ethylmaleimide-sensitive fusion protein attachment receptor protein complex of synaptosomal-associated protein of 25 kDa (SNAP-25), syntaxin 1, and vesicle-associated membrane protein 2. Ethylmaleimide 77-93 synaptosome associated protein 25 Homo sapiens 201-208 14529723-2 2003 One potential downstream target of PKC in the presynaptic terminal is the soluble N-ethylmaleimide sensitive factor (NSF) attachment protein receptor (SNARE) SNAP-25, which has a PKC phosphorylation site in its C-terminal coil centered at serine 187 (S187/Ser187). Ethylmaleimide 82-98 synaptosome associated protein 25 Homo sapiens 158-165 11751907-3 2002 The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins syntaxin, SNAP-25, and synaptobrevin are central components of the fusion apparatus. Ethylmaleimide 14-28 synaptosome associated protein 25 Homo sapiens 101-108 12417653-3 2002 We studied the only PKC-dependent phosphorylation site in the neuronal soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, Ser(187), in synaptosome-associated protein of 25 kDa (SNAP-25). Ethylmaleimide 79-95 synaptosome associated protein 25 Homo sapiens 171-211 12417653-3 2002 We studied the only PKC-dependent phosphorylation site in the neuronal soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, Ser(187), in synaptosome-associated protein of 25 kDa (SNAP-25). Ethylmaleimide 79-95 synaptosome associated protein 25 Homo sapiens 213-220 12164547-8 2002 Several presynaptic thiol-containing proteins (e.g. SNAP-25, NSF) are critically involved in formation of SNARE (soluble N-ethylmaleimide (NEM)-sensitive fusion protein receptor) complexes that mediate membrane fusion processes such as exocytosis and turnover of plasmalemmal proteins and other constituents. Ethylmaleimide 121-137 synaptosome associated protein 25 Homo sapiens 52-59 10085240-1 1999 The tSNARE (the target-membrane soluble NSF-attachment protein receptor, where NSF is N-ethylmaleimide-sensitive fusion protein) synaptosomal-associated protein of 25 kDa (SNAP-25) is expressed in pancreatic B-cells and its cleavage by botulinum neurotoxin E (BoNT/E) abolishes stimulated secretion of insulin. Ethylmaleimide 86-102 synaptosome associated protein 25 Homo sapiens 129-170 10600650-1 2000 The neuronal N-ethylmaleimide-sensitive-factor-attachment-protein receptor (SNARE) proteins 25-kDa synaptosomal protein (SNAP-25), syntaxin 1 and synaptobrevin 2 interact to form the intermembrane SNARE complex, which mediates docking and fusion of synaptic vesicles with the plasma membrane. Ethylmaleimide 13-29 synaptosome associated protein 25 Homo sapiens 121-128 10085240-1 1999 The tSNARE (the target-membrane soluble NSF-attachment protein receptor, where NSF is N-ethylmaleimide-sensitive fusion protein) synaptosomal-associated protein of 25 kDa (SNAP-25) is expressed in pancreatic B-cells and its cleavage by botulinum neurotoxin E (BoNT/E) abolishes stimulated secretion of insulin. Ethylmaleimide 86-102 synaptosome associated protein 25 Homo sapiens 172-179 32602955-5 2020 RESULTS: Following injection into tissues, onabotulinumtoxinA inhibits soluble N-ethylmaleimide-sensitive fusion attachment protein receptor (SNARE)-mediated vesicle trafficking by cleaving one of its essential proteins, soluble N-ethylmaleimide-sensitive fusion attachment protein (SNAP-25), which occurs in both motor and sensory nerves. Ethylmaleimide 79-95 synaptosome associated protein 25 Homo sapiens 283-290 9614185-1 1998 The importance of soluble N-ethyl maleimide (NEM)-sensitive fusion protein (NSF) attachment protein (SNAP) receptors (SNAREs) in synaptic vesicle exocytosis is well established because it has been demonstrated that clostridial neurotoxins (NTs) proteolyze the vesicle SNAREs (v-SNAREs) vesicle-associated membrane protein (VAMP)/brevins and their partners, the target SNAREs (t-SNAREs) syntaxin 1 and SNAP25. Ethylmaleimide 26-43 synaptosome associated protein 25 Homo sapiens 401-407 35167762-2 2022 In this model, the soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein (SNAP) receptor (SNARE) proteins syntaxin-1, SNAP-25, and synaptobrevin form tight complexes that bring the membranes together and are crucial for membrane fusion. Ethylmaleimide 27-43 synaptosome associated protein 25 Homo sapiens 131-138 11830673-2 2002 The vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein synaptobrevin 2 and the plasma membrane SNAREs syntaxin 1 and synaptosomal protein of 25 kDa (SNAP-25) are essential for calcium-triggered exocytosis. Ethylmaleimide 22-38 synaptosome associated protein 25 Homo sapiens 162-192 27734716-1 2017 Synaptosomal-associated protein 25 kDa (SNAP-25) is one of the key proteins involved in the formation of neural soluble N-ethylmaleimide-sensitive factor attachment protein receptor complexes, which are responsible for the calcium-dependent exocytosis of neurotransmitters - a major step in neurotransmission and the key to normal functioning of brain. Ethylmaleimide 122-136 synaptosome associated protein 25 Homo sapiens 0-38 30544779-1 2018 Synaptic vesicle fusion is mediated by an assembly of soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptors (SNAREs), composed of syntaxin 1, soluble NSF-attachment protein (SNAP)-25, and synaptobrevin-2/VAMP-2. Ethylmaleimide 62-78 synaptosome associated protein 25 Homo sapiens 167-207 27734716-1 2017 Synaptosomal-associated protein 25 kDa (SNAP-25) is one of the key proteins involved in the formation of neural soluble N-ethylmaleimide-sensitive factor attachment protein receptor complexes, which are responsible for the calcium-dependent exocytosis of neurotransmitters - a major step in neurotransmission and the key to normal functioning of brain. Ethylmaleimide 122-136 synaptosome associated protein 25 Homo sapiens 40-47 22525946-1 2012 Interactions between the proteins of the ternary soluble N-ethyl maleimide-sensitive fusion protein attachment protein receptor (SNARE) complex, synaptobrevin 2 (Sb2), syntaxin 1A (Sx1A) and synaptosome-associated protein of 25 kDa (SNAP25) can be readily assessed using force spectroscopy single-molecule measurements. Ethylmaleimide 57-74 synaptosome associated protein 25 Homo sapiens 191-231 28339008-4 2017 Genes for soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) annotated with the function "vesicle" were identified and one of these proteins, synaptosomal-associated protein 25 (SNAP25), was found to have significantly lower expression levels in MB. Ethylmaleimide 18-34 synaptosome associated protein 25 Homo sapiens 171-205 28339008-4 2017 Genes for soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) annotated with the function "vesicle" were identified and one of these proteins, synaptosomal-associated protein 25 (SNAP25), was found to have significantly lower expression levels in MB. Ethylmaleimide 18-34 synaptosome associated protein 25 Homo sapiens 207-213 28137749-1 2017 The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein syntaxin-1 adopts a closed conformation when bound to Munc18-1, preventing binding to synaptobrevin-2 and SNAP-25 to form the ternary SNARE complex. Ethylmaleimide 14-28 synaptosome associated protein 25 Homo sapiens 196-203 22525946-1 2012 Interactions between the proteins of the ternary soluble N-ethyl maleimide-sensitive fusion protein attachment protein receptor (SNARE) complex, synaptobrevin 2 (Sb2), syntaxin 1A (Sx1A) and synaptosome-associated protein of 25 kDa (SNAP25) can be readily assessed using force spectroscopy single-molecule measurements. Ethylmaleimide 57-74 synaptosome associated protein 25 Homo sapiens 233-239 21844343-1 2011 Exocytosis of synaptic vesicles (SVs) during fast synaptic transmission is mediated by soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex assembly formed by the coil-coiling of three members of this protein family: vesicle SNARE protein, synaptobrevin 2 (syb2), and the presynaptic membrane SNAREs syntaxin-1A and SNAP-25. Ethylmaleimide 95-111 synaptosome associated protein 25 Homo sapiens 349-356