PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8744943-1	1996	The cysteine residues involved in the class I disulfide bonds between the alpha subunits in the (alpha beta)2 dimer of the human insulin receptor have been identified by labeling with N-ethylmaleimide and by site-directed mutagenesis.	Ethylmaleimide	184-200	insulin receptor	Homo sapiens	129-145	
2822020-2	1987	The insulin-receptor kinase was observed to be more sensitive to inhibition by N-ethylmaleimide in the presence [IC50 (concn, giving 50% inhibition) = 25 +/- 3 microM] than in the absence (IC50 = 73 +/- 6 microM) of insulin.	Ethylmaleimide	79-95	insulin receptor	Homo sapiens	4-20	
3026782-2	1987	The labeling of this protein was greatly increased by concurrent treatment of the cells with N-ethylmaleimide, to the extent that the amount of [125I]-insulin cross-linked to the enzyme in these cells was approximately 20 to 50% that cross-linked to the insulin receptor.	Ethylmaleimide	93-109	insulin receptor	Homo sapiens	254-270	
3510210-5	1986	Treatment of the plasma membrane with N-ethylmaleimide (NEM) has two effects; 1) NEM prevents the formation of a larger form (greater than 350,000 daltons) of the phosphorylated insulin receptor.	Ethylmaleimide	38-54	insulin receptor	Homo sapiens	178-194	
3510210-5	1986	Treatment of the plasma membrane with N-ethylmaleimide (NEM) has two effects; 1) NEM prevents the formation of a larger form (greater than 350,000 daltons) of the phosphorylated insulin receptor.	Ethylmaleimide	56-59	insulin receptor	Homo sapiens	178-194	
2985615-6	1985	The src kinase-catalyzed phosphorylation of the insulin receptor is not due to the activation of receptor autophosphorylation because a N-ethylmaleimide-treated receptor preparation devoid of receptor kinase activity is also phosphorylated by the src kinase.	Ethylmaleimide	136-152	insulin receptor	Homo sapiens	48-64	
3891757-5	1985	Treatment of the insulin receptor preparations with oxidized glutathione or N-ethylmaleimide prior to SDS-polyacrylamide gel electrophoresis increased the relative amount of the alpha 2 beta 2 complex concomitant with a total disappearance of the alpha 2 beta, alpha 2 beta 1, alpha 2, and free beta forms.	Ethylmaleimide	76-92	insulin receptor	Homo sapiens	17-33	
7045574-5	1982	Crude solubilized insulin receptor from human placenta is contaminated with "insulinase" which is inhibited by N-ethylmaleimide.	Ethylmaleimide	111-127	insulin receptor	Homo sapiens	18-34