PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11934672-2	2002	Exposure of betaHC9 cells to a Krebs-Ringer bicarbonate-HEPES buffer (KRBH) made hypotonic by a reduction of 25 mM NaCl resulted in a prompt stimulation of insulin release.	HEPES	56-61	insulin	Homo sapiens	156-163	
9653630-8	1998	Only in HEPES buffer was good discrimination between the investigated insulin formulations observed.	HEPES	8-13	insulin	Homo sapiens	70-77	
6582851-12	1983	The different results in the different buffers, indicate that a buffer containing Hepes and/or Tris, is required to expose negative cooperativity and make the receptors more accessible to insulin.	HEPES	82-87	insulin	Homo sapiens	188-195	
6339685-2	1983	The conditions for insulin binding to fibroblasts were optimal and employed HEPES binding buffer, pH 8.0 at 15 degrees C for 5 h. These conditions correspond to those previously employed with monocytes from MyD subjects.	HEPES	76-81	insulin	Homo sapiens	19-26