PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14979662-5	2004	PDGF-AB, TGF-beta1 and IL-8 provoke conformational changes in mollusk immunocytes, involving the signaling transduction pathways of phosphatidylinositol and cAMP.	Phosphatidylinositols	132-152	C-X-C motif chemokine ligand 8	Homo sapiens	23-27	
17121804-0	2007	Rhinovirus activates interleukin-8 expression via a Src/p110beta phosphatidylinositol 3-kinase/Akt pathway in human airway epithelial cells.	Phosphatidylinositols	65-85	C-X-C motif chemokine ligand 8	Homo sapiens	21-34	
15358661-5	2004	Treatment of T24 and 5637 cells with phosphatidylinositol-specific phospholipase C to eliminate CD14 from the cell surface dramatically suppressed the induction of IL-8.	Phosphatidylinositols	37-57	C-X-C motif chemokine ligand 8	Homo sapiens	164-168	
2839752-5	1988	NaF plus AlCl3 induced increases in inositol tris-, bis-, and mono-phosphates and decreases in PtdIns(4,5)P2, phosphatidylinositol 4-phosphate, and phosphatidylinositol within 5 min after addition to the cytotoxin-treated cells at 37 C. GTP gamma S stimulated, to some extent, polyphosphoinositide hydrolysis in the cytotoxin-treated JURKAT.	Phosphatidylinositols	110-130	C-X-C motif chemokine ligand 8	Homo sapiens	0-3	
8971982-3	1996	With membranes exposed to exogenous labeled phosphoinositides, activation of phospholipase C with calcium, with G-proteins stimulated by GTP gamma S or NaF, or with several receptor agonists, have demonstrated that all of the components of the phosphoinositide system are retained in human brain membranes and are responsive to appropriate stimuli.	Phosphatidylinositols	44-61	C-X-C motif chemokine ligand 8	Homo sapiens	152-155	
8971982-3	1996	With membranes exposed to exogenous labeled phosphoinositides, activation of phospholipase C with calcium, with G-proteins stimulated by GTP gamma S or NaF, or with several receptor agonists, have demonstrated that all of the components of the phosphoinositide system are retained in human brain membranes and are responsive to appropriate stimuli.	Phosphatidylinositols	44-60	C-X-C motif chemokine ligand 8	Homo sapiens	152-155	
1654060-3	1991	PGI2 synthesis by NaF-stimulated endothelial cells was associated with increases in arachidonate release, phosphoinositide hydrolysis, generation of inositol phosphates, and accumulation of diacylglycerol.	Phosphatidylinositols	106-122	C-X-C motif chemokine ligand 8	Homo sapiens	18-21	
1851210-3	1991	Ethanol exposure reduced guanosine 5"-O-(3-thiotriphosphate) [GTP(S)]- and, to a lesser extent, NaF/AlCl3-stimulated phosphoinositide hydrolysis, whereas it had no effect on the enzymatic activity of a phosphatidylinositol 4,5-bisphosphate-specific phospholipase C. [3H]Bradykinin binding in the absence of GTP(S) was not influenced by ethanol exposure.	Phosphatidylinositols	117-133	C-X-C motif chemokine ligand 8	Homo sapiens	96-99	
12975484-3	2003	The putative Ins(1,4,5)P3 receptor antagonist 2-aminoethoxydiphenyl borane reduced the response to CXCR2 activation by interleukin-8, as did sustained inhibition of phosphatidylinositol 4-kinase with wortmannin, suggesting the involvement of phosphoinositides in the potentiation.	Phosphatidylinositols	242-259	C-X-C motif chemokine ligand 8	Homo sapiens	119-132	
9473671-6	1998	Glutathione depletion also potentiated the inhibition by H2O2 of carbachol- or G-protein (NaF)-stimulated phosphoinositide hydrolysis, whereas phospholipase C activated by the calcium ionophore ionomycin was not inhibited.	Phosphatidylinositols	106-122	C-X-C motif chemokine ligand 8	Homo sapiens	90-93	
9473671-7	1998	The thiol-oxidizing agent diamide also inhibited phosphoinositide hydrolysis stimulated by carbachol or NaF, and glutathione depletion potentiated the diamide concentration-dependent inhibition.	Phosphatidylinositols	49-65	C-X-C motif chemokine ligand 8	Homo sapiens	104-107	
24510965-9	2014	Overexpression of AGS3 in RBL-CXCR2 significantly inhibited CXCL8-induced Ca(2+) mobilization, phosphoinositide hydrolysis, and chemotaxis.	Phosphatidylinositols	95-111	C-X-C motif chemokine ligand 8	Homo sapiens	60-65