PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32397331-0 2020 Patterned Superhydrophobic SERS Substrates for Sample Pre-Concentration and Demonstration of Its Utility through Monitoring of Inhibitory Effects of Paraoxon and Carbaryl on AChE. Carbaryl 162-170 acetylcholinesterase (Cartwright blood group) Homo sapiens 174-178 6849937-1 1983 Acetylcholinesterase (acetylcholine acetylhydrolase, EC 3.1.1.7), phosphorylated with dichlorvos, showed relatively more reactivity toward the substrate indophenyl acetate than the enzyme that was carbamylated with carbaryl. Carbaryl 215-223 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 5971773-2 1966 The kinetics of acetylcholinesterase (EC 3.1.1.7) activity and its inhibition by eserine or by Sevin (1-naphthyl N-methylcarbamate) have been studied over the substrate concentration range 5x10(-8) to 2.5x10(-2)m. 2. Carbaryl 102-130 acetylcholinesterase (Cartwright blood group) Homo sapiens 16-36 32397331-10 2020 Inhibitory effects of paraoxon and carbaryl on AChE were evaluated from the TC peak intensity. Carbaryl 35-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 47-51 31353389-10 2019 Furthermore, pesticide carbaryl as an inhibitor of AChE activity was detected. Carbaryl 23-31 acetylcholinesterase (Cartwright blood group) Homo sapiens 51-55 24770986-3 2014 Chitosan was used as the enzyme immobilization material, and AChE was used as the model enzyme for carbaryl detection to fabricate AChE biosensor. Carbaryl 99-107 acetylcholinesterase (Cartwright blood group) Homo sapiens 131-135 26314619-4 2015 We studied two different pesticides, chlorpyrifos and carbaryl, which specifically inhibit acetylcholinesterase (AChE) in the nervous system. Carbaryl 54-62 acetylcholinesterase (Cartwright blood group) Homo sapiens 91-111 26314619-4 2015 We studied two different pesticides, chlorpyrifos and carbaryl, which specifically inhibit acetylcholinesterase (AChE) in the nervous system. Carbaryl 54-62 acetylcholinesterase (Cartwright blood group) Homo sapiens 113-117 25461134-6 2015 Based on the inhibition of OPs on AChE activity, the sensor showed wide linear ranges of 7.98-2.00x10(3)pgmL(-1) and 4.3-1.00x10(3)pgmL(-1) with low detection limits of 4.14pgmL(-1) and 1.15pgmL(-1) for malathion and carbaryl, respectively. Carbaryl 217-225 acetylcholinesterase (Cartwright blood group) Homo sapiens 34-38 24770986-0 2014 Acetylcholinesterase biosensor for carbaryl detection based on interdigitated array microelectrodes. Carbaryl 35-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 24770986-3 2014 Chitosan was used as the enzyme immobilization material, and AChE was used as the model enzyme for carbaryl detection to fabricate AChE biosensor. Carbaryl 99-107 acetylcholinesterase (Cartwright blood group) Homo sapiens 61-65 24770986-5 2014 Based on the inhibition of pesticides on the AChE activity, using carbaryl as model compounds, the biosensor exhibited a wide range, low detection limit, and high stability. Carbaryl 66-74 acetylcholinesterase (Cartwright blood group) Homo sapiens 45-49 21738917-4 2011 Further, based on the inhibition of OPs on the enzymatic activity of the immobilized AChE, and using carbaryl as a model compound, the inhibition of carbaryl was proportional to its concentration ranging from 0.001 to 0.015 and 0.015 to 2 mug mL(-1) with a detection limit of 0.3 ng mL(-1) (S/N = 3). Carbaryl 101-109 acetylcholinesterase (Cartwright blood group) Homo sapiens 85-89 23962483-5 2013 It became evident that pralidoxime and obidoxime in therapeutic concentrations aggravate the inhibition of AChE by carbaryl and propoxur, with obidoxime being substantially more potent compared to 2-PAM. Carbaryl 115-123 acetylcholinesterase (Cartwright blood group) Homo sapiens 107-111 21937528-0 2012 Effects of dichlorvos and carbaryl on the activity of free and immobilized acetylcholinesterase. Carbaryl 26-34 acetylcholinesterase (Cartwright blood group) Homo sapiens 75-95 21937528-2 2012 The purpose of this study was to examine the effect of carbaryl and dichlorvos on the activity of AChE. Carbaryl 55-63 acetylcholinesterase (Cartwright blood group) Homo sapiens 98-102 21937528-13 2012 AChE activity of free form is more affected by carbaryl (0.11 +- 0.01 mM/ml/min) than immobilized form (0.1 +- 0.04 mM/ml/min). Carbaryl 47-55 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 21937528-14 2012 Comparison of mean AChE activity showed that the activity of the enzyme in presence of dichlorvos and carbaryl was significantly lower compared to controls. Carbaryl 102-110 acetylcholinesterase (Cartwright blood group) Homo sapiens 19-23 21937528-16 2012 The results of our study indicate that dichlorvos and carbaryl cause decrease in AChE activity for both free and immobilization form of enzyme. Carbaryl 54-62 acetylcholinesterase (Cartwright blood group) Homo sapiens 81-85 21937528-17 2012 It is therefore concluded that measuring AChE activity is a way to evaluate poisoning with carbaryl and dichlorvos. Carbaryl 91-99 acetylcholinesterase (Cartwright blood group) Homo sapiens 41-45 22684846-5 2013 Therefore we examined the effect of five different pesticides (carbaryl, carbofuran, parathion, demeton-S-methyl, and aldicarb) on AChE activity to determine whether combinations had an additive, synergistic, or antagonistic inhibitory effect. Carbaryl 63-71 acetylcholinesterase (Cartwright blood group) Homo sapiens 131-135 21738917-4 2011 Further, based on the inhibition of OPs on the enzymatic activity of the immobilized AChE, and using carbaryl as a model compound, the inhibition of carbaryl was proportional to its concentration ranging from 0.001 to 0.015 and 0.015 to 2 mug mL(-1) with a detection limit of 0.3 ng mL(-1) (S/N = 3). Carbaryl 149-157 acetylcholinesterase (Cartwright blood group) Homo sapiens 85-89 17590326-4 2007 Four pesticides of carbaryl, malathion, dimethoate and monocrotophos were selected to discuss their inhibition efficiencies to AChE. Carbaryl 19-27 acetylcholinesterase (Cartwright blood group) Homo sapiens 127-131 21601034-4 2011 Based on the inhibition of OPs on the enzymatic activity of the immobilized AChE, and used carbaryl as the model compound, the resulting biosensor exhibits excellent performance for OPs detection including good reproducibility, acceptable stability, and a reliable linear relationship between the inhibition and log[carbaryl] from 2 ng mL-1 up to 2 mug mL-1 with a detection limit of 0.7 ng mL-1,which provides a new promising tool for analysis of enzyme inhibitors. Carbaryl 91-99 acetylcholinesterase (Cartwright blood group) Homo sapiens 76-80 21601034-4 2011 Based on the inhibition of OPs on the enzymatic activity of the immobilized AChE, and used carbaryl as the model compound, the resulting biosensor exhibits excellent performance for OPs detection including good reproducibility, acceptable stability, and a reliable linear relationship between the inhibition and log[carbaryl] from 2 ng mL-1 up to 2 mug mL-1 with a detection limit of 0.7 ng mL-1,which provides a new promising tool for analysis of enzyme inhibitors. Carbaryl 316-324 acetylcholinesterase (Cartwright blood group) Homo sapiens 76-80 16256972-7 2006 Furthermore, activity of AChE, but not NTE, was significantly inhibited by aldicarb and carbaryl in differentiating cells, which suggested that cytoskeletal protein changes induced by carbamate esters in differentiating cells was associated with inhibition of AChE but not NTE. Carbaryl 88-96 acetylcholinesterase (Cartwright blood group) Homo sapiens 25-29 17723768-5 2006 AChE-based biosensors have demonstrated a higher sensitivity towards aldicarb (50% inhibition with 50 ppb) and carbaryl (50% inhibition with 85 ppb) while BChE biosensors have shown a higher affinity towards paraoxon (50% inhibition with 4 ppb) and chlorpyrifos-methyl oxon (50% inhibition with 1 ppb). Carbaryl 111-119 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 16256972-7 2006 Furthermore, activity of AChE, but not NTE, was significantly inhibited by aldicarb and carbaryl in differentiating cells, which suggested that cytoskeletal protein changes induced by carbamate esters in differentiating cells was associated with inhibition of AChE but not NTE. Carbaryl 88-96 acetylcholinesterase (Cartwright blood group) Homo sapiens 260-264 9568379-0 1998 Effects of hexamethonium, phenothiazines, propranolol and ephedrine on acetylcholinesterase carbamylation by physostigmine, aldicarb and carbaryl: interaction between the active site and the functionally distinct peripheral sites in acetylcholinesterase. Carbaryl 137-145 acetylcholinesterase (Cartwright blood group) Homo sapiens 71-91 9568379-0 1998 Effects of hexamethonium, phenothiazines, propranolol and ephedrine on acetylcholinesterase carbamylation by physostigmine, aldicarb and carbaryl: interaction between the active site and the functionally distinct peripheral sites in acetylcholinesterase. Carbaryl 137-145 acetylcholinesterase (Cartwright blood group) Homo sapiens 233-253 9568379-1 1998 Physostigmine, aldicarb and carbaryl were potent inhibitors of acetylcholinesterase (AChE). Carbaryl 28-36 acetylcholinesterase (Cartwright blood group) Homo sapiens 63-83 9568379-1 1998 Physostigmine, aldicarb and carbaryl were potent inhibitors of acetylcholinesterase (AChE). Carbaryl 28-36 acetylcholinesterase (Cartwright blood group) Homo sapiens 85-89 35533565-0 2022 A green photocatalytic-biosensor for colorimetric detection of pesticide (carbaryl) based on inhibition of acetylcholinesterase. Carbaryl 74-82 acetylcholinesterase (Cartwright blood group) Homo sapiens 107-127 1412499-4 1992 We have found that the inhibition of both eel acetylcholinesterase (eel AChE, EC 3.1.1.7) and human serum cholinesterase (human BuChE, EC 3.1.1.8) by carbaryl was enhanced by several oximes. Carbaryl 150-158 acetylcholinesterase (Cartwright blood group) Homo sapiens 72-76 1842792-6 1991 Studies of the in vitro inhibition of acetylcholinesterase (AChE) activity by carbaryl demonstrated that there was no difference between males and females of a given strain and that the R strain AChE was considerably less sensitive to inhibition. Carbaryl 78-86 acetylcholinesterase (Cartwright blood group) Homo sapiens 38-58 1842792-6 1991 Studies of the in vitro inhibition of acetylcholinesterase (AChE) activity by carbaryl demonstrated that there was no difference between males and females of a given strain and that the R strain AChE was considerably less sensitive to inhibition. Carbaryl 78-86 acetylcholinesterase (Cartwright blood group) Homo sapiens 60-64 8561923-3 1995 In vivo inhibition of whole body AChE reveals higher degree of inhibition by LD50 dose of Methyl parathion as compared to that of Carbaryl where maximum inhibition was noticed at the agricultural dose. Carbaryl 130-138 acetylcholinesterase (Cartwright blood group) Homo sapiens 33-37 35533565-5 2022 But the activity of AChE will be suppressed by carbaryl, thus generating less thiocholine and resulting in more ox-TMB for colorimetric analysis. Carbaryl 47-55 acetylcholinesterase (Cartwright blood group) Homo sapiens 20-24 35588856-4 2022 Upon optimum conditions, the constructed AChE sensor showed an ultrahigh sensitivity (0.279 muA/nM), a wide linear range (9.44 x 10-8 - 0.944 mg/L) and a low detection limit (9.44 x 10-8 mg/L) for carbaryl. Carbaryl 197-205 acetylcholinesterase (Cartwright blood group) Homo sapiens 41-45