PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15957946-2 2005 The common THP ring system was stereoselectively constructed through a SmI(2)-induced reductive cyclization of beta-alkoxy acrylate 5 followed by Mitsunobu inversion, and each chiral center at C-10 was created by Brown"s asymmetric allylation. pirarubicin 11-14 homeobox C10 Homo sapiens 193-197