PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20357441-8 2010 Furthermore, paclitaxel and pirarubicin suppressed the expression of PCNA, cyclin D1, cyclin E and Bcl-2, and increased Bax expression. pirarubicin 28-39 BCL2 associated X, apoptosis regulator Homo sapiens 120-123 20357441-9 2010 CONCLUSION: These results suggest that the G2/M or G0/G1 cell cycle arrest and apoptosis induced by paclitaxel and pirarubicin are Bcl-2/Bax dependent, suggesting favorable effects of combination therapy with paclitaxel and pirarubicin in the treatment of osteosarcoma. pirarubicin 115-126 BCL2 associated X, apoptosis regulator Homo sapiens 137-140 20357441-9 2010 CONCLUSION: These results suggest that the G2/M or G0/G1 cell cycle arrest and apoptosis induced by paclitaxel and pirarubicin are Bcl-2/Bax dependent, suggesting favorable effects of combination therapy with paclitaxel and pirarubicin in the treatment of osteosarcoma. pirarubicin 224-235 BCL2 associated X, apoptosis regulator Homo sapiens 137-140 20193328-10 2009 The changes of expression of bcl-2 and bax and decreasing of the bcl-2/bax ratio may be an important mechanism of action of the intravesical instillation of THP for preventing recurrence of non-muscle invasive bladder cancer. pirarubicin 157-160 BCL2 associated X, apoptosis regulator Homo sapiens 39-42 20193328-10 2009 The changes of expression of bcl-2 and bax and decreasing of the bcl-2/bax ratio may be an important mechanism of action of the intravesical instillation of THP for preventing recurrence of non-muscle invasive bladder cancer. pirarubicin 157-160 BCL2 associated X, apoptosis regulator Homo sapiens 71-74