PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21076398-0 2011 Cardiac glycosides are potent inhibitors of interferon-beta gene expression. Glycosides 8-18 interferon beta 1 Homo sapiens 44-59 21076398-1 2011 Here we report that bufalin and other cardiac glycoside inhibitors of the sodium-potassium ATPase (sodium pump) potently inhibit the induction of the interferon-beta (IFNbeta) gene by virus, double-stranded RNA or double-stranded DNA. Glycosides 46-55 interferon beta 1 Homo sapiens 150-165 21076398-1 2011 Here we report that bufalin and other cardiac glycoside inhibitors of the sodium-potassium ATPase (sodium pump) potently inhibit the induction of the interferon-beta (IFNbeta) gene by virus, double-stranded RNA or double-stranded DNA. Glycosides 46-55 interferon beta 1 Homo sapiens 167-174 21076398-2 2011 Cardiac glycosides increase the intracellular sodium concentration, which appears to inhibit the ATPase activity of the RNA sensor RIG-I, an essential and early component in the IFNbeta activation pathway. Glycosides 8-18 interferon beta 1 Homo sapiens 178-185