PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15009100-2	2004	In contrast to a previous report, we found that anthralin induced time- and concentration-dependent phosphorylation of epidermal growth factor receptor in primary human keratinocytes.	Anthralin	48-57	epidermal growth factor receptor	Homo sapiens	119-151	
15009100-5	2004	Second, there is a correlation between a time-dependent increase in anthralin-induced epidermal growth factor receptor phosphorylation and H(2)O(2) generation.	Anthralin	68-77	epidermal growth factor receptor	Homo sapiens	86-118	
15009100-6	2004	Third, the structurally different antioxidants n-propyl gallate and N-acetylcysteine inhibited epidermal growth factor receptor phosphorylation induced by anthralin.	Anthralin	155-164	epidermal growth factor receptor	Homo sapiens	95-127	
15009100-8	2004	The epidermal growth factor receptor-specific tyrosine kinase inhibitor PD153035 abrogated anthralin-induced epidermal growth factor receptor phosphorylation and activation of extracellular-regulated kinase 1/2.	Anthralin	91-100	epidermal growth factor receptor	Homo sapiens	4-36	
15009100-8	2004	The epidermal growth factor receptor-specific tyrosine kinase inhibitor PD153035 abrogated anthralin-induced epidermal growth factor receptor phosphorylation and activation of extracellular-regulated kinase 1/2.	Anthralin	91-100	epidermal growth factor receptor	Homo sapiens	109-141	
15009100-10	2004	Our data identify anthralin-induced reactive oxygen species and, more specifically, H(2)O(2) as an important upstream mediator required for ligand-independent epidermal growth factor receptor phosphorylation and downstream signaling.	Anthralin	18-27	epidermal growth factor receptor	Homo sapiens	159-191