PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29966873-1 2018 The new aminoalkyl-substituted derivatives of known CK2 inhibitors 4,5,6,7-tetrabromo-1H-benzimidazole (TBBi) and 4,5,6,7-tetrabromo-1H-benzotriazole (TBBt) were synthesized, and their influence on the activity of recombinant human CK2 alpha, CK2 holoenzyme and PIM1 kinases was evaluated. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 114-149 casein kinase 2 alpha 2 Homo sapiens 232-241 25891901-1 2015 The interaction of human CK2alpha (hCK2alpha) with nine halogenated benzotriazoles, TBBt and its analogues representing all possible patterns of halogenation on the benzene ring of benzotriazole, was studied by biophysical methods. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 84-88 casein kinase 2 alpha 2 Homo sapiens 25-33 25891901-1 2015 The interaction of human CK2alpha (hCK2alpha) with nine halogenated benzotriazoles, TBBt and its analogues representing all possible patterns of halogenation on the benzene ring of benzotriazole, was studied by biophysical methods. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 84-88 casein kinase 2 alpha 2 Homo sapiens 35-44 18258654-6 2008 Utilizing a chemoproteomics approach in conjunction with inhibitor-resistant mutant studies, CK2alpha and CK2alpha" were identified as bona fide targets of TBB, TBBz, and DMAT in cells. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 156-159 casein kinase 2 alpha 2 Homo sapiens 93-101 23155426-5 2012 The role of halogen bonding remains debatable, as originally noted for the crystal structure of TBBt with CK2alpha (pdb1j91). 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 96-100 casein kinase 2 alpha 2 Homo sapiens 106-114 25450618-1 2015 The interaction of human CK2alpha with a series of tetrabromobenzotriazole (TBBt) and tetrabromobenzimidazole (TBBz) analogs, in which one of the bromine atoms proximal to the triazole/imidazole ring is replaced by a methyl group, was studied by biochemical (IC50) and biophysical methods (thermal stability of protein-ligand complex monitored by DSC and fluorescence). 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 76-80 casein kinase 2 alpha 2 Homo sapiens 25-33 18258654-6 2008 Utilizing a chemoproteomics approach in conjunction with inhibitor-resistant mutant studies, CK2alpha and CK2alpha" were identified as bona fide targets of TBB, TBBz, and DMAT in cells. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 156-159 casein kinase 2 alpha 2 Homo sapiens 106-114