PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29966873-1	2018	The new aminoalkyl-substituted derivatives of known CK2 inhibitors 4,5,6,7-tetrabromo-1H-benzimidazole (TBBi) and 4,5,6,7-tetrabromo-1H-benzotriazole (TBBt) were synthesized, and their influence on the activity of recombinant human CK2 alpha, CK2 holoenzyme and PIM1 kinases was evaluated.	2-ethylhexyl 2,3,4,5-tetrabromobenzoate	114-149	casein kinase 2 alpha 2	Homo sapiens	232-241	
25891901-1	2015	The interaction of human CK2alpha (hCK2alpha) with nine halogenated benzotriazoles, TBBt and its analogues representing all possible patterns of halogenation on the benzene ring of benzotriazole, was studied by biophysical methods.	2-ethylhexyl 2,3,4,5-tetrabromobenzoate	84-88	casein kinase 2 alpha 2	Homo sapiens	25-33	
25891901-1	2015	The interaction of human CK2alpha (hCK2alpha) with nine halogenated benzotriazoles, TBBt and its analogues representing all possible patterns of halogenation on the benzene ring of benzotriazole, was studied by biophysical methods.	2-ethylhexyl 2,3,4,5-tetrabromobenzoate	84-88	casein kinase 2 alpha 2	Homo sapiens	35-44	
25450618-1	2015	The interaction of human CK2alpha with a series of tetrabromobenzotriazole (TBBt) and tetrabromobenzimidazole (TBBz) analogs, in which one of the bromine atoms proximal to the triazole/imidazole ring is replaced by a methyl group, was studied by biochemical (IC50) and biophysical methods (thermal stability of protein-ligand complex monitored by DSC and fluorescence).	2-ethylhexyl 2,3,4,5-tetrabromobenzoate	76-80	casein kinase 2 alpha 2	Homo sapiens	25-33	
23155426-5	2012	The role of halogen bonding remains debatable, as originally noted for the crystal structure of TBBt with CK2alpha (pdb1j91).	2-ethylhexyl 2,3,4,5-tetrabromobenzoate	96-100	casein kinase 2 alpha 2	Homo sapiens	106-114	
18258654-6	2008	Utilizing a chemoproteomics approach in conjunction with inhibitor-resistant mutant studies, CK2alpha and CK2alpha" were identified as bona fide targets of TBB, TBBz, and DMAT in cells.	2-ethylhexyl 2,3,4,5-tetrabromobenzoate	156-159	casein kinase 2 alpha 2	Homo sapiens	93-101	
18258654-6	2008	Utilizing a chemoproteomics approach in conjunction with inhibitor-resistant mutant studies, CK2alpha and CK2alpha" were identified as bona fide targets of TBB, TBBz, and DMAT in cells.	2-ethylhexyl 2,3,4,5-tetrabromobenzoate	156-159	casein kinase 2 alpha 2	Homo sapiens	106-114