PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17935135-7 2008 Using TBB, an inhibitor of protein kinase CK2, we showed that CK2 was required for hypoxia-induced HDAC activation. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 6-9 histone deacetylase 9 Homo sapiens 99-103 17935135-12 2008 Use of Apicidin (an HDAC inhibitor) and TBB revealed that CK2-dependent HDAC activation contributed to pVHL downregulation and HIF-1alpha stabilization under hypoxia. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 40-43 histone deacetylase 9 Homo sapiens 72-76 32218358-3 2020 Using tetrabromobenzotriazole (TBB) and 2-dimethylamino-4,5,6,7-tetrabromo-benzimidazole (DMAT) as scaffolds for CK2 inhibition, and a hydroxamate to coordinate the zinc atom present in the active site of HDAC (zinc binding group, ZBG), new multitarget inhibitors have been designed and synthesized. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate 31-34 histone deacetylase 9 Homo sapiens 205-209