PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2847557-5	1988	Cyclooxygenase inhibition alone (either indomethacin or sodium meclofenamate) resulted in active, nonflow-dependent pulmonary vasoconstriction.	Meclofenamic Acid	56-76	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	0-14	
2508492-2	1989	Our specific objective was to characterize the effects of two chemically dissimilar inhibitors of the cyclooxygenase pathway, indomethacin and sodium meclofenamate, on the pulmonary vascular P/Q relationship measured in conscious and pentobarbital-anesthetized dogs.	Meclofenamic Acid	143-163	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	102-116	
2508492-6	1989	Cyclooxygenase pathway inhibition with either indomethacin (5 mg/kg iv) or meclofenamate (2.5 mg/kg iv) resulted in active, flow-independent pulmonary vasoconstriction (P less than 0.01) in both conscious and pentobarbital-anesthetized dogs.	Meclofenamic Acid	75-88	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	0-14	
3142275-3	1988	Cyclooxygenase inhibition (COI) was induced by 40 microM indomethacin (n = 4) or 45 microM meclofenamate (n = 4) before 5-HT infusion in a second group (5-HTCOI; n = 8).	Meclofenamic Acid	91-104	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	0-14	
3159511-11	1985	These data indicate that the combination of endothelial injury and cyclooxygenase inhibition with indomethacin or meclofenamate results in proximal coronary artery vasoconstriction.	Meclofenamic Acid	114-127	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	67-81	
3084759-4	1986	However, in dogs pretreated with indomethacin (5 mg/kg) or sodium meclofenamate (3 mg/kg), inhibitors of cyclooxygenase, hydralazine injection resulted in an increase in renal artery blood flow of only 44 +/- 5.3 ml/min (19 +/- 2.7%) from 235 +/- 23 ml/min, an increase significantly different from that in control dogs (P less than .05).	Meclofenamic Acid	59-79	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	105-119	
3920919-4	1985	In rings of femoral and pulmonary vein contracted with norepinephrine, arachidonic acid produced a concentration-dependent increase in tension that was eliminated by removal of the endothelium or by treatment with the inhibitors of cyclooxygenase (indomethacin, meclofenamate, or acetylsalicyclic acid).	Meclofenamic Acid	262-275	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	232-246	
7846106-6	1994	Cyclooxygenase inhibition by either indomethacin or meclofenamate (10(-6) M) did not influence ACh release.	Meclofenamic Acid	52-65	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	0-14	
1539679-5	1992	Prior treatment of the cells in culture with the cyclooxygenase inhibitor, sodium meclofenamate (4 microM), markedly reduced the relaxant effect of the conditioned buffer, whereas prior treatment with MK-886, an inhibitor of 5-lipoxygenase, did not alter relaxant activity.	Meclofenamic Acid	75-95	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	49-63	
11208767-17	2001	Finally, inhibition of both COX isoforms with meclofenamate, in dogs treated with L-NAME (n=6), completely prevented the vasodilator and excretory actions of BK.	Meclofenamic Acid	46-59	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	28-31