PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27879648-1	2016	Deoxycytidine kinase (dCK) is a key enzyme in deoxyribonucleoside salvage and the anti-tumor activity for many nucleoside analogs.	Deoxyribonucleosides	46-65	deoxycytidine kinase	Homo sapiens	0-20	
27811125-1	2017	18F-clofarabine, a nucleotide purine analog, is a substrate for deoxycytidine kinase (dCK), a key enzyme in the deoxyribonucleoside salvage pathway.	Deoxyribonucleosides	112-131	deoxycytidine kinase	Homo sapiens	64-84	
16361699-2	2006	Deoxycytidine kinase (dCK) catalyzes the rate-limiting step of the deoxyribonucleoside salvage pathway in mammalian cells and plays a key role in the activation of numerous nucleoside analogues used in anti-cancer and antiviral chemotherapy.	Deoxyribonucleosides	67-86	deoxycytidine kinase	Homo sapiens	0-20	
21127859-1	2011	PURPOSE: Deoxycytidine kinase (dCK) is a rate-limiting enzyme in deoxyribonucleoside salvage, a metabolic pathway involved in the production and maintenance of a balanced pool of deoxyribonucleoside triphosphates (dNTPs) for DNA synthesis.	Deoxyribonucleosides	65-84	deoxycytidine kinase	Homo sapiens	9-29	
21413197-9	2004	Phosphorylation of deoxyribonucleosides and their nucleoside analogs is carried out with deoxycytidine kinase (DCK) (5).	Deoxyribonucleosides	19-39	deoxycytidine kinase	Homo sapiens	89-109	
21413197-9	2004	Phosphorylation of deoxyribonucleosides and their nucleoside analogs is carried out with deoxycytidine kinase (DCK) (5).	Deoxyribonucleosides	19-39	deoxycytidine kinase	Homo sapiens	111-114	
27035974-1	2016	Deoxycytidine kinase (dCK), a rate-limiting enzyme in the cytosolic deoxyribonucleoside (dN) salvage pathway, is an important therapeutic and positron emission tomography (PET) imaging target in cancer.	Deoxyribonucleosides	68-87	deoxycytidine kinase	Homo sapiens	0-20	
27035974-1	2016	Deoxycytidine kinase (dCK), a rate-limiting enzyme in the cytosolic deoxyribonucleoside (dN) salvage pathway, is an important therapeutic and positron emission tomography (PET) imaging target in cancer.	Deoxyribonucleosides	89-91	deoxycytidine kinase	Homo sapiens	0-20	
20544527-1	2010	Deoxycytidine kinase (dCK) is a key enzyme in the salvage of deoxyribonucleosides and in the activation of several anticancer and antiviral nucleoside analogues.	Deoxyribonucleosides	61-81	deoxycytidine kinase	Homo sapiens	0-20	
15571256-1	2004	Deoxycytidine kinase (dCK) is essential for the phosphorylation of several deoxyribonucleosides and various analogues such as gemcitabine (2",2"-difluorodeoxycytidine).	Deoxyribonucleosides	75-95	deoxycytidine kinase	Homo sapiens	0-20	
17065079-1	2006	Compelling evidence suggests that deoxycytidine kinase (dCK), a key enzyme in the salvage of deoxyribonucleosides and in the activation of clinically relevant nucleoside analogues, can be regulated by reversible phosphorylation.	Deoxyribonucleosides	93-113	deoxycytidine kinase	Homo sapiens	34-54	
8790720-1	1996	The mammalian deoxyribonucleoside kinases thymidine kinase 1 and 2, deoxycytidine kinase and deoxyguanosine kinase phosphorylate deoxyribonucleosides and provide an alternative to de novo synthesis of DNA precursors.	Deoxyribonucleosides	129-149	deoxycytidine kinase	Homo sapiens	68-88	
12566083-1	2003	Deoxycytidine kinase (dCK) catalyses the rate-limiting step of the salvage of three natural deoxyribonucleosides as well as several therapeutic nucleoside analogues, which in turn can enhance its enzymatic activity [Biochem Pharmacol 56 (1998) 1175], improving the efficacy of the cytostatic therapy.	Deoxyribonucleosides	92-112	deoxycytidine kinase	Homo sapiens	0-20	
12628850-1	2003	Deoxycytidine kinase (dCK) is required for the phosphorylation of several deoxyribonucleoside analogues that are widely employed as chemotherapeutic agents.	Deoxyribonucleosides	74-93	deoxycytidine kinase	Homo sapiens	0-20	
2163272-1	1990	Deoxycytidine kinase, purified from human leukemic spleen to apparent homogeneity, is a multisubstrate enzyme that also phosphorylates purine deoxyribonucleosides [Bohman & Eriksson (1988) Biochemistry 27, 4258-4265].	Deoxyribonucleosides	142-162	deoxycytidine kinase	Homo sapiens	0-20	
8421671-1	1993	Deoxycytidine kinase (NTP:deoxycytidine 5"-phosphotransferase, EC 2.7.1.74) is an enzyme that catalyzes phosphorylation of deoxyribonucleosides and a number of nucleoside analogs that are important in antiviral and cancer chemotherapy.	Deoxyribonucleosides	123-143	deoxycytidine kinase	Homo sapiens	0-20	
1657002-1	1991	Three key enzymes in the anabolic phosphorylation of deoxyribonucleosides and deoxyribonucleoside analogs were purified i.e. cytoplasmic thymidine kinase (TK1), mitochondrial thymidine kinase (TK2) and cytoplasmic deoxycytidine kinase (dCK) from human, mouse and monkey liver and spleen.	Deoxyribonucleosides	53-73	deoxycytidine kinase	Homo sapiens	214-234