PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8453949-4	1993	Acetazolamide (a CA blocker) was used for the pretreatment of normal mice to compare them to CA deficient littermates.	Acetazolamide	0-13	carbonic anhydrase 2	Mus musculus	17-19	
3093210-0	1986	Induction of new carbonic anhydrase II following treatment with acetazolamide in DBA and C57 mice.	Acetazolamide	64-77	carbonic anhydrase 2	Mus musculus	17-38	
3093210-3	1986	The percentage increases in CA II fluorescent intensity of cells from C57 mice treated with 40 and 200 mg/kg acetazolamide over those of untreated mice were 22 and 36%, respectively, after 1 day, 32 and 40%, respectively, after 3 days, and 17 and 40%, respectively, after 5 days of treatment.	Acetazolamide	109-122	carbonic anhydrase 2	Mus musculus	28-33	
3093210-6	1986	In C57 mice the maximum amount of CA II per cell at each dose occurred 24 h after acetazolamide treatment, whereas the amount in DBA mice continued to increase with time and dose up to 5 days.	Acetazolamide	82-95	carbonic anhydrase 2	Mus musculus	34-39	
21524585-4	2011	Results indicated that nine target compounds exhibit as effectively as acetazolamide and 10 compounds have more potent inhibition effects on carbonic anhydrase II than acetazolamide.	Acetazolamide	168-181	carbonic anhydrase 2	Mus musculus	141-162	
2494045-6	1989	Accompanying the development of tolerance to the anticonvulsant effects of AZM was an increase in both the activity and specific activity of CAII in the various subcellular fractions and areas of the brain.	Acetazolamide	75-78	carbonic anhydrase 2	Mus musculus	141-145	
2494045-8	1989	Tolerance to the EST-elevating effects of AZM correlated with increases in the activity, total amount, and specific activity of CAII in the myelin fraction of the cerebral cortex.	Acetazolamide	42-45	carbonic anhydrase 2	Mus musculus	128-132	
29973405-7	2018	Experiments in glioma xenograft mouse models demonstrated that the CAII inhibitor acetazolamide enhanced survival of TMZ-treated animals.	Acetazolamide	82-95	carbonic anhydrase 2	Mus musculus	67-71