PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33177988-11	2020	We identified that the probable clearance effect of hepcidin on alpha-syn was mediated by the autophagy pathway using pretreatment with autophagy inhibitors (3-MA and CQ) and detection of autophagy protein markers (LC3II/I and p62).	3-methyladenine	158-162	synuclein alpha	Homo sapiens	64-73	
12868068-8	2003	Both cell viability and the increase in alpha-synuclein expression are prevented by antioxidants; by the specific inhibitors of p38 and SAPK/JNK, SB203580 and SP600125, respectively; and by the inhibitor of autophagy 3-methyladenine.	3-methyladenine	217-232	synuclein alpha	Homo sapiens	40-55	
34848256-8	2021	In Lamp2-knock down cells, pathologic alpha-synuclein was increased 12 h after DQ treatment, but there was no change observed at 24 h. In DQ-treated cells, macroautophagy by 3-methyladenine and bafilomycin inhibition increased Lamp2A expression, indicating an increase in CMA activity.	3-methyladenine	174-189	synuclein alpha	Homo sapiens	38-53	
31165943-4	2019	Meanwhile, we observed that the clearance of alpha-Syn by astrocytes was abolished by proteasome inhibitor MG132 and autophagy inhibitor 3-methyladenine (3MA).	3-methyladenine	137-152	synuclein alpha	Homo sapiens	45-54	
32517337-7	2020	The vasicinone mediated autophagy pathways were abrogated by treatment with the autophagy inhibitor 3-MA, which lead to increases alpha-synuclein accumulation and decreased the expression of p-ULK and ATG proteins and the autophagy marker LC3-II compared to that observed without 3-MA treatment.	3-methyladenine	100-104	synuclein alpha	Homo sapiens	130-145	
31165943-4	2019	Meanwhile, we observed that the clearance of alpha-Syn by astrocytes was abolished by proteasome inhibitor MG132 and autophagy inhibitor 3-methyladenine (3MA).	3-methyladenine	154-157	synuclein alpha	Homo sapiens	45-54	
31165943-5	2019	We further showed that intracellular alpha-Syn was reduced after ginkgolide B (GB) and bilobalide (BB) treatment, and the decrease was reversed by MG132 and 3MA.	3-methyladenine	157-160	synuclein alpha	Homo sapiens	37-46	
29214369-5	2018	Surprisingly, GK, but not GB, promoted the clearance of A53T alpha-syn, which can be abolished by autophagy inhibitor 3-methyladenine, indicating that GK-induced autophagy intervened in the clearance of A53T alpha-syn.	3-methyladenine	118-133	synuclein alpha	Homo sapiens	61-70	
19864570-6	2009	The effects of beclin 1 overexpression on LC3 and alpha-syn accumulation were partially blocked by 3-MA and completely blocked by bafilomycin A1.	3-methyladenine	99-103	synuclein alpha	Homo sapiens	50-59	
29896416-8	2018	After addition of the autophagy inhibitor 3-MA, the protective effect of SIRT3 diminished: the cell viability decreased, while the apoptosis rate increased; alpha-synuclein accumulation enhanced; ROS production increased; antioxidants levels, including SOD and GSH, decreased; and MMP collapsed.	3-methyladenine	42-46	synuclein alpha	Homo sapiens	157-172	
30693689-7	2018	When curcumin and 3-MA were given concurrently, the number of surviving dopamine neurons, protein expression of TFEB, LAMP2A and LC3-II increased (P<0.05 or P<0.01), and both protein expression and mRNA expression of alpha-Syn decreased (P<0.05 or P<0.01) compared with MPTP model group; but the number of surviving dopamine neurons and protein expression of LAMP2A and LC3-II decreased compared with curcumin group (all P<0.05).	3-methyladenine	18-22	synuclein alpha	Homo sapiens	217-226