PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31176046-8	2019	Autophagy inhibitor 3-MA blocked the protective effects of PG in mediating NLRP3 inflammasome and IL-1beta processing.	3-methyladenine	20-24	interleukin 1 alpha	Homo sapiens	98-106	
34052845-8	2021	In vivo, 3-MA and LY294002 repressed Ti particle-stimulated osteolysis and osteoclastogenesis and reduced expression of the pro-inflammatory factors TNF-alpha, IL-1beta, and IL-6.	3-methyladenine	9-13	interleukin 1 alpha	Homo sapiens	160-168	
32010254-9	2020	The expression levels of NLRP3, caspase-1 and IL-1beta were inhibited after the addition of autophagy inhibitor 3-MA.	3-methyladenine	112-116	interleukin 1 alpha	Homo sapiens	46-54	
32104285-12	2020	Under LPS treatment, the NF-kappaB pathway inhibitor BAY11-7082 further enhanced the inhibitory effects of rapamycin, but inhibited the promoting effects of 3-MA on the protein expression levels of IL-1beta and caspase-1.	3-methyladenine	157-161	interleukin 1 alpha	Homo sapiens	198-206	
32015215-5	2020	These effects were reversed by treatment with the early autophagy inhibitor 3-methyl adenine, which suggests HO-1-induced autophagy suppresses IL-1beta-induced apoptosis in NPCs.	3-methyladenine	76-92	interleukin 1 alpha	Homo sapiens	143-151	
16644476-7	2006	Moreover, another PI3K inhibitor 3-methyladenine also strongly enhanced IL-1-induced NF-kappaB DNA binding, while LY303511, an inactive analogue of LY29, did not increase the NF-kappaB DNA binding.	3-methyladenine	33-48	interleukin 1 alpha	Homo sapiens	72-76	
34565256-5	2021	The results showed that LPS induced NF-kappaB-related pulmonary inflammation in observers and silicosis patients, as confirmed by an increase in the expression of IL-1beta, IL-6, TNF-alpha, and p65, which could be inhibited by 3-MA treatment.	3-methyladenine	227-231	interleukin 1 alpha	Homo sapiens	163-171	
34492927-5	2021	Besides, both 3-MA and CQ addition increased NLRP3, Caspase-1, NEK7, ASC, GSDMA, GSDME, IL-1beta, IL-18 mRNA levels, NLRP3, Caspase-1 p20, ASC, GSDMD protein and ROS levels, and NO, LDH, IL-1beta, IL-18 releases.	3-methyladenine	14-18	interleukin 1 alpha	Homo sapiens	88-96	
34492927-5	2021	Besides, both 3-MA and CQ addition increased NLRP3, Caspase-1, NEK7, ASC, GSDMA, GSDME, IL-1beta, IL-18 mRNA levels, NLRP3, Caspase-1 p20, ASC, GSDMD protein and ROS levels, and NO, LDH, IL-1beta, IL-18 releases.	3-methyladenine	14-18	interleukin 1 alpha	Homo sapiens	187-195