PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33034415-15 2021 The results showed that when 3-MA and BafA1 were applied, the promotion of autophagy by zinc was blocked and that the inhibitory effect of zinc on NLRP3 was reversed. 3-methyladenine 29-33 NLR family, pyrin domain containing 3 Mus musculus 147-152 34010608-8 2021 Inhibiting autophagy with 3-MA reversed the inhibition of NLRP3 inflammasome activation and diminished the neuroprotective effects of Gas6. 3-methyladenine 26-30 NLR family, pyrin domain containing 3 Mus musculus 58-63 34530204-15 2021 Inhibition of autophagy by 3-MA treatment also promoted the activity of NLRP3 inflammasome and the production of IL-1beta and IL-18. 3-methyladenine 27-31 NLR family, pyrin domain containing 3 Mus musculus 72-77 35628508-7 2022 RAPA treatment (an inducer of autophagy) significantly improved realgar-induced liver injury and NLRP3 inflammasome activation, while 3-MA (an inhibitor of autophagy) aggravated the realgar-induced liver injury and NLRP3 inflammasome activation. 3-methyladenine 134-138 NLR family, pyrin domain containing 3 Mus musculus 97-102 35628508-7 2022 RAPA treatment (an inducer of autophagy) significantly improved realgar-induced liver injury and NLRP3 inflammasome activation, while 3-MA (an inhibitor of autophagy) aggravated the realgar-induced liver injury and NLRP3 inflammasome activation. 3-methyladenine 134-138 NLR family, pyrin domain containing 3 Mus musculus 215-220 33987329-8 2021 Furthermore, 3-methyladenine, an autophagy inhibitor, abolished lycopene"s inhibitory effect on the NLRP3 inflammasome in KCs, which led to increased hepatic IR injury. 3-methyladenine 13-28 NLR family, pyrin domain containing 3 Mus musculus 100-105 35354793-10 2022 Adding the autophagy inhibitor 3-methyladenine or chloroquine attenuated the inhibitory effect of Irisin on beta-GP-induced ROS production, NLRP3 inflammasome activation, pyroptosis, and calcification in VSMCs. 3-methyladenine 31-46 NLR family, pyrin domain containing 3 Mus musculus 140-145 33895270-9 2021 Treatment with 3-MA, an autophagy inhibitor, eliminated the neuroprotective effects of SAHA on improving cognition in mice, activating autophagy and downregulating the NLRP3 inflammasome. 3-methyladenine 15-19 NLR family, pyrin domain containing 3 Mus musculus 168-173 33717152-11 2021 Furthermore, Parkin deletion or pretreated with 3MA (autophagy inhibitor) exacerbated these detrimental actions of IH, which was accompanied with NLRP3 inflammasome activation. 3-methyladenine 48-51 NLR family, pyrin domain containing 3 Mus musculus 146-151 33217525-10 2021 Moreover, autophagy inhibitor 3-methyladenine (3MA) attenuated PAT-induced increase in cytoplasmic cathepsin B expression, and subsequent LDH release, the activation of NLRP3 inflamosomes, pyroptotic cell death, and inflammation. 3-methyladenine 30-45 NLR family, pyrin domain containing 3 Mus musculus 169-174 33217525-10 2021 Moreover, autophagy inhibitor 3-methyladenine (3MA) attenuated PAT-induced increase in cytoplasmic cathepsin B expression, and subsequent LDH release, the activation of NLRP3 inflamosomes, pyroptotic cell death, and inflammation. 3-methyladenine 47-50 NLR family, pyrin domain containing 3 Mus musculus 169-174 30254716-11 2018 Both Sirt3-siRNA and autophagy inhibitor 3-MA partially abolished the beneficial effects of melatonin on mitoROS clearance and NLRP3 inflammasome activation, indicating the crucial role of Sirt3-mediated mitophagy. 3-methyladenine 41-45 NLR family, pyrin domain containing 3 Mus musculus 127-132 30918581-11 2019 Using 3-MA, an autophagy inhibitor, the neuroprotective effects of HNK on mitophagy and NLRP3 inflammasome activation were eliminated. 3-methyladenine 6-10 NLR family, pyrin domain containing 3 Mus musculus 88-93