PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14668580-3 2004 Omapatrilat, a VasoPeptidase-inhibitor, selectively inhibits both Neutral-Endo-Peptidase (NEP) and ACE. omapatrilat 0-11 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 99-102 12745671-0 2003 Omapatrilat, an angiotensin-converting enzyme and neutral endopeptidase inhibitor, attenuates early atherosclerosis in diabetic and in nondiabetic low-density lipoprotein receptor-deficient mice. omapatrilat 0-11 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 16-45 12745671-1 2003 Omapatrilat inhibits both angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP). omapatrilat 0-11 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 26-55 12745671-1 2003 Omapatrilat inhibits both angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP). omapatrilat 0-11 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 57-60 11254898-0 2001 Omapatrilat, a dual angiotensin-converting enzyme and neutral endopeptidase inhibitor, prevents fatty streak deposit in apolipoprotein E-deficient mice. omapatrilat 0-11 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 20-49 16208151-9 2005 Omapatrilat conferred superior renoprotection in the diabetic apo E-KO mouse compared with quinapril in the context of greater renal ACE inhibition by omapatrilat than seen with quinapril, additional renal NEP inhibition and a modestly enhanced antihypertensive response. omapatrilat 0-11 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 133-136 16208151-12 2005 These results suggest that the anti-atherosclerotic effect conferred by omapatrilat treatment in the diabetic apo E-KO mouse is predominantly mediated by its capacity to inhibit local vascular ACE. omapatrilat 72-83 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 193-196 16208151-13 2005 By contrast, in the kidney, local renal ACE and NEP inhibition and the superior antihypertensive effect of omapatrilat all contribute to the renoprotective effect conferred by omapatrilat treatment in the diabetic apo E-KO mouse. omapatrilat 176-187 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 40-43 34304582-2 2021 Omapatrilat, a dual NEP inhibitor-ACE inhibitor, was a promising antihypertensive drug but failed in trials due to angioedema, an effect possibly caused by inhibition of both the N- and C-domains of ACE. omapatrilat 0-11 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 34-37 34304582-2 2021 Omapatrilat, a dual NEP inhibitor-ACE inhibitor, was a promising antihypertensive drug but failed in trials due to angioedema, an effect possibly caused by inhibition of both the N- and C-domains of ACE. omapatrilat 0-11 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 199-202