PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12618234-6 2003 Rats treated with omapatrilat and captopril had reduced cardiac BNP mRNA levels and less myocardial fibrosis by comparison with the vehicle-treated rats. omapatrilat 18-29 natriuretic peptide B Rattus norvegicus 64-67 15791290-5 2005 Only omapatrilat increased both peak BNP and peak cGMP upon reperfusion, those increases being blocked by Hoe-140. omapatrilat 5-16 natriuretic peptide B Rattus norvegicus 37-40 15659305-4 2005 In the plasma and myocardium, omapatrilat treatment increased BNP contents, reduced NEP activity; in myocardium, mRNA level of proBNP and corin decreased, but NEP mRNA expression increased. omapatrilat 30-41 natriuretic peptide B Rattus norvegicus 62-65 15659305-5 2005 Our study confirmed that omapatrilat treated myocardial necrosis effectively and suggested that increased BNP in rats with myocardial necrosis could depend on increased production and conversion as well as decreased degradation. omapatrilat 25-36 natriuretic peptide B Rattus norvegicus 106-109 26184548-5 2015 Omapatrilat treatment normalized the BNP and reduced the BP by 45 mm Hg in the NX rats. omapatrilat 0-11 natriuretic peptide B Rattus norvegicus 37-40