PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24982238-0 2014 Inhibitory action of levocetirizine on the production of eosinophil chemoattractants RANTES and eotaxin in vitro and in vivo. levocetirizine 21-35 C-C motif chemokine ligand 11 Homo sapiens 96-103 24982238-8 2014 The addition of levocetirizine to eosinophil cultures caused a dose-dependent decrease in the ability of cells to produce RANTES and eotaxin in response to antigen stimulation, and the minimum concentration that caused a significant decrease was 0.05 muM. levocetirizine 16-30 C-C motif chemokine ligand 11 Homo sapiens 133-140 24982238-10 2014 Oral administration of levocetirizine for four weeks also reduced RANTES and eotaxin levels in nasal secretions from patients with pollinosis, along with attenuation of clinical symptoms. levocetirizine 23-37 C-C motif chemokine ligand 11 Homo sapiens 77-84 24982238-11 2014 The ability of levocetirizine to reduce RANTES and eotaxin levels may account, at least in part, for the clinical efficacy of the agent for allergic disorders, including allergic rhinitis. levocetirizine 15-29 C-C motif chemokine ligand 11 Homo sapiens 51-58 15298570-9 2004 In vitro, endothelial cells produced eotaxin mRNA and protein product in a dose- and time-dependent fashion following incubation with histamine, an effect that was blocked by levocetirizine. levocetirizine 175-189 C-C motif chemokine ligand 11 Homo sapiens 37-44 12190657-0 2002 Cetirizine and levocetirizine inhibit eotaxin-induced eosinophil transendothelial migration through human dermal or lung microvascular endothelial cells. levocetirizine 15-29 C-C motif chemokine ligand 11 Homo sapiens 38-45 12190657-8 2002 Pre-incubation of eosinophils with cetirizine or levocetirizine dose-dependently inhibited eosinophil TEM to eotaxin through both HMVEC-d or HMVEC-l with total inhibition of eotaxin-induced TEM observed at 10-8 m for HMVEC-d and 10-7 m for HMVEC-l. levocetirizine 49-63 C-C motif chemokine ligand 11 Homo sapiens 109-116 12190657-8 2002 Pre-incubation of eosinophils with cetirizine or levocetirizine dose-dependently inhibited eosinophil TEM to eotaxin through both HMVEC-d or HMVEC-l with total inhibition of eotaxin-induced TEM observed at 10-8 m for HMVEC-d and 10-7 m for HMVEC-l. levocetirizine 49-63 C-C motif chemokine ligand 11 Homo sapiens 174-181 12190657-12 2002 CONCLUSION: Levocetirizine inhibits eotaxin-induced eosinophil TEM through both dermal and lung microvascular endothelial cells suggesting that, like cetirizine, levocetirizine has potential anti-inflammatory effects. levocetirizine 12-26 C-C motif chemokine ligand 11 Homo sapiens 36-43 12190657-12 2002 CONCLUSION: Levocetirizine inhibits eotaxin-induced eosinophil TEM through both dermal and lung microvascular endothelial cells suggesting that, like cetirizine, levocetirizine has potential anti-inflammatory effects. levocetirizine 162-176 C-C motif chemokine ligand 11 Homo sapiens 36-43